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Jakob Reiser

Researcher at Center for Biologics Evaluation and Research

Publications -  82
Citations -  8856

Jakob Reiser is an academic researcher from Center for Biologics Evaluation and Research. The author has contributed to research in topics: Transduction (genetics) & Gene. The author has an hindex of 42, co-authored 81 publications receiving 8455 citations. Previous affiliations of Jakob Reiser include National Institutes of Health & University of Zurich.

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Journal ArticleDOI

Transfer of proteins from gels to diazobenzyloxymethyl-paper and detection with antisera: a method for studying antibody specificity and antigen structure

TL;DR: A rapid and very sensitive method for detecting proteins as antigens after their separation in polyacrylamide/agarose composite gels, with or without sodium dodecyl sulfate.
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Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors.

TL;DR: Improved protocols to generate highly concentrated lentiviral vector pseudotypes involving different envelope glycoproteins are described, which result in high-titer vector preparations that show reduced toxicity compared with lentIViral vectors produced using standard protocols involving ultracentrifugation-based methods.
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Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa

TL;DR: The RhLR-RhlI regulatory system was found to be essential for the production of elastase as well, and cross-communication between the RhlR- RhlI rhamnolipid regulatory system and the LasR-LasIElastase elastases regulatory systemwas demonstrated.
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Altering the tropism of lentiviral vectors through pseudotyping.

TL;DR: This review samples a few of the more prominent examples from the ever-expanding list of published lentiviral pseudotypes, noting comparisons made with pseudotypes involving VSV-G in terms of titer, viral particle stability, toxicity, and host-cell specificity.
Book ChapterDOI

[15] Detection of specific RNAs or specific fragments of DNA by fractionation in gels and transfer to diazobenzyloxymethyl paper

TL;DR: The efficiency of transfer is very high and independent of the size of a fragment as covalent linkage allows convenient multiple reuse of the transfers and also allows washings to be done repeatedly under stringent conditions, thereby helping to achieve very low backgrounds.