J
James A. Birchler
Researcher at University of Missouri
Publications - 328
Citations - 18204
James A. Birchler is an academic researcher from University of Missouri. The author has contributed to research in topics: Gene & Chromosome. The author has an hindex of 60, co-authored 314 publications receiving 16583 citations. Previous affiliations of James A. Birchler include Indiana University & South Dakota State University.
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Journal ArticleDOI
Understanding mechanisms of novel gene expression in polyploids.
Thomas C. Osborn,J. Chris Pires,James A. Birchler,Donald L. Auger,Z. Jeffery Chen,Hyeon Se Lee,Luca Comai,Andreas Madlung,Rebecca W. Doerge,Vincent Colot,Robert A. Martienssen +10 more
TL;DR: Polyploidy has long been recognized as a prominent force shaping the evolution of eukaryotes, especially flowering plants, and new phenotypes often arise with polyploid formation.
Journal Article
RNAi-mediated pathways in the nucleus
Marjori Matzke,James A. Birchler +1 more
TL;DR: RNA interference is an evolutionarily conserved mechanism that uses short antisense RNAs that are generated by 'dicing' dsRNA precursors to target corresponding mRNAs for cleavage to facilitate the directed silencing of specific genomic regions.
Journal ArticleDOI
RNAi-mediated pathways in the nucleus
Marjori Matzke,James A. Birchler +1 more
TL;DR: RNA interference (RNAi) is an evolutionarily conserved mechanism that uses short antisense RNAs that are generated by 'dicing' dsRNA precursors to target corresponding mRNAs for cleavage as discussed by the authors.
Journal ArticleDOI
Heterochromatic Silencing and HP1 Localization in Drosophila Are Dependent on the RNAi Machinery
Manika Pal-Bhadra,Manika Pal-Bhadra,Boris A. Leibovitch,Sumit G. Gandhi,Madhusudana Rao,Utpal Bhadra,Utpal Bhadra,James A. Birchler,Sarah C. R. Elgin +8 more
TL;DR: It is demonstrated that this silencing is dependent on the RNA interference machinery, using tandem mini-white arrays and white transgenes in heterochromatin to show loss of silencing as a result of mutations in piwi, aubergine, or spindle-E (homeless), which encode RNAi components.
Journal ArticleDOI
Chromosome painting using repetitive DNA sequences as probes for somatic chromosome identification in maize
TL;DR: A multicolor fluorescence in situ hybridization procedure was developed that identifies meiotic pachytene, late prophase I, and metaphase I chromosomes and could facilitate the study of chromosomal structure and behavior and be adapted for other plant species.