J
James A. G. Whitworth
Researcher at University of London
Publications - 247
Citations - 15832
James A. G. Whitworth is an academic researcher from University of London. The author has contributed to research in topics: Population & Acquired immunodeficiency syndrome (AIDS). The author has an hindex of 64, co-authored 246 publications receiving 14903 citations. Previous affiliations of James A. G. Whitworth include Uganda Virus Research Institute & Department for International Development.
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Journal ArticleDOI
Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies.
Esther E. Freeman,Helen A. Weiss,Judith R. Glynn,Pamela L Cross,James A. G. Whitworth,Richard J. Hayes +5 more
TL;DR: Prevalent HSV-2 infection is associated with a three-fold increased risk of HIV acquisition among both men and women in the general population, suggesting that, in areas of high HSVs-2 prevalence, a high proportion of HIV is attributable to HSv-2.
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Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum.
Tim J. Anderson,Bernhard Haubold,Jeff T. Williams,Jose G. Estrada-Franco,Lynne Richardson,Rene Mollinedo,Moses J. Bockarie,John L. Mokili,Sungano Mharakurwa,Neil French,James A. G. Whitworth,Iván D. Vélez,Alan Brockman,François Nosten,Marcelo U. Ferreira,Karen P. Day +15 more
TL;DR: The intraspecific patterns of diversity and genetic differentiation observed in P. falciparum are strikingly similar to those seen in interspecific comparisons of plants and animals with differing levels of outcrossing, suggesting that similar processes may be involved.
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Effect of HIV-1 and increasing immunosuppression on malaria parasitaemia and clinical episodes in adults in rural Uganda: a cohort study
James A. G. Whitworth,Dilys Morgan,Maria A Quigley,Adrian Smith,Billy N. Mayanja,Henry Eotu,Nicholas Omoding,Martin Okongo,Samuel S. Malamba,A. Ojwiya +9 more
TL;DR: HIV-1 infection is associated with an increased frequency of clinical malaria and parasitaemia, and this association tends to become more pronounced with advancing immunosuppression, and could have important public-health implications for sub-Saharan Africa.
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23–valent pneumococcal polysaccharide vaccine in HIV-1-infected Ugandan adults: double-blind, randomised and placebo controlled trial
Neil French,Neil French,Jessica Nakiyingi,Lucy M. Carpenter,Lucy M. Carpenter,E. Lugada,Christine Watera,K Moi,M Moore,M Moore,D Antvelink,Daan W. Mulder,Edward N. Janoff,James A. G. Whitworth,Charles F. Gilks +14 more
TL;DR: 23-valent pneumococcal polysaccharide vaccination is ineffective in HIV-1-infected Ugandan adults and probably has little, or no, public health value elsewhere in sub-Saharan Africa.
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HIV-1 infection in rural Africa: is there a difference in median time to AIDS and survival compared with that in industrialized countries?
TL;DR: Survival with HIV-1 infection is similar in Africa to industrialized countries before the use of antiretroviral therapy; when they do die, many of those in Africa are severely immunosuppressed and most have clinical features of AIDS.