J
James J. Collins
Researcher at Massachusetts Institute of Technology
Publications - 700
Citations - 105255
James J. Collins is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Synthetic biology & Population. The author has an hindex of 151, co-authored 669 publications receiving 89476 citations. Previous affiliations of James J. Collins include Baylor College of Medicine & University at Albany, SUNY.
Papers
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Journal ArticleDOI
And the Noise Played on: Stochastic Gene Expression and HIV-1 Infection
TL;DR: It is shown that fluctuations in a key regulator, Tat, in an isogenic population of infected cells result in two distinct expression states corresponding to latent and productive HIV-1 infection.
Journal ArticleDOI
The Impact of Vaccination Efforts on the Spatiotemporal Patterns of the Hepatitis A Outbreak in Michigan, 2016-2018.
Andrew F. Brouwer,Jonathan L. Zelner,Marisa C. Eisenberg,Lynsey Kimmins,Macey Ladisky,James J. Collins,Joseph N. S. Eisenberg +6 more
TL;DR: Investigating how vaccine timing and coverage influenced the spatiotemporal patterns of the largest hepatitis A virus outbreak in the United States found the value of targeting populations where local transmission is not yet sustained rather than populations where transmission is already waning.
Patent
Proton-motive force stimulation to potentiate aminoglycoside antibiotics against persistent bacteria
TL;DR: In this article, compositions and methods to improve treatment of chronic infections, and reduce, delay, or inhibit formation of biofilms, using specific combinations of aminoglycoside antibiotics and high, localized concentrations of one or more PMF stimulating compounds.
Book Chapter
Classifying migrants in the field of health: sociolinguistic scale and neoliberal statecraft
Patent
Biological analog-to-digital and digital-to-analog converter switches
James J. Collins,Timothy K. Lu +1 more
TL;DR: In this article, the authors describe novel biological converter switches that utilize modular components, such as genetic toggle switches and single invertase memory modules (SIMMs), for converting analog inputs to digital outputs, and digital inputs to analog outputs, in cells and cellular systems.