James J. Collins

TL;DR: This paper found that genetic loss of let-7 is common in neuroblastoma, inversely associated with myCN amplification, and independently associated with poor outcomes, providing a rationale for chromosomal loss patterns in NC.

TL;DR: In this article, the authors systematically dissected the cellular factors involved in provirus repression in embryonic carcinomas (ECs) and ESCs by a genome-wide siRNA screen, and reported a genomewide atlas of functional nodes that mediate proviral silencing in ESCs and illuminates the comprehensive, interconnected, and multi-layered genetic and epigenetic mechanisms by which ESCs repress retroviruses within the genome.

TL;DR: This study analyzes COP trajectories as one-dimensional and two-dimensional random walks to reveal that over short-term intervals of time during undisturbed stance the COP behaves as a positively correlated random walk, whereas over long-term interval of time it resembles a negatively correlated randomWalk.

TL;DR: The results suggest that the intestinal pathogen S. typhimurium can intercept indole signaling from the commensal bacterium E. coli to enhance its antibiotic tolerance in the host intestine.