James J. Collins

TL;DR: This Timeline article charts the technological and cultural lifetime of synthetic biology, with an emphasis on key breakthroughs and future challenges.

TL;DR: This in vitro model replicated results from past animal and human studies, including demonstration that probiotic and antibiotic therapies can suppress villus injury induced by pathogenic bacteria and proof-of-principle to show that the microfluidic gut-on-a-chip device can be used to create human intestinal disease models and gain new insights into gut pathophysiology.

TL;DR: Scientists working on the response of bacteria to antibiotics define antibiotic persistence and provide practical guidance on how to study bacterial persister cells, and provide a guide to measuring persistence.

TL;DR: A model describing the regulation of gene expression and the effects of noise are developed and it is suggested that an external noise source could be used as a switch and/or amplifier for gene expression.

TL;DR: It is shown that increased variability in gene expression, affected by the sequence of the TATA box, can be beneficial after an acute change in environmental conditions.