J
James J. Collins
Researcher at Massachusetts Institute of Technology
Publications - 700
Citations - 105255
James J. Collins is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Synthetic biology & Population. The author has an hindex of 151, co-authored 669 publications receiving 89476 citations. Previous affiliations of James J. Collins include Baylor College of Medicine & University at Albany, SUNY.
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Engineered enzymatically active bacteriophage and methods for dispersing biofilms
James J. Collins,Timothy K. Lu +1 more
TL;DR: The present invention is directed to engineered enzymatically active bacteriophages that are both capable of killing the bacteria by lysis and dispersing the bacterial biofilm because they have been also engineered to express biofilm-degrading enzymes, particularly dispersin B (DspB) as discussed by the authors.
Journal ArticleDOI
Serum concentrations of chlorinated dibenzo-p-dioxins and dibenzofurans among former Michigan trichlorophenol and pentachlorophenol workers.
James J. Collins,Kenneth M. Bodner,Michael Wilken,Salma Haidar,Carol J. Burns,Robert A. Budinsky,Greg D. Martin,Michael L. Carson,J. Craig Rowlands +8 more
TL;DR: The Worker Referent group had higher levels of dioxins and furans than the Community Referents indicating the potential for exposure outside the chlorophenol departments at the site, and these data can be used to better assess dioxin exposures in future health studies.
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Control of Clostridium difficile infection by defined microbial communities
TL;DR: The epidemiology and physiology of C. difficile infection is summarized, the current understanding of how fecal microbiota transplants treat recurrent CDI is described, and potential ways that knowledge can be used to rationally design and test alternative microbe-based therapeutics are outlined.
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Transformation by Simian Virus 40 of Spleen Cells from a Hyperimmune Rabbit: Evidence for Synthesis of Immunoglobulin by the Transformed Cells
TL;DR: Spleen cells derived from a rabbit hyperimmunized with a Type III pneumococcal vaccine were exposed to simian virus 40 in vitro and transformed cells had a morphology characteristic of cells transformed by simianirus 40.
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Mass Spectrometry Imaging and Identification of Peptides Associated with Cephalic Ganglia Regeneration in Schmidtea mediterranea
Ta-Hsuan Ong,Elena V. Romanova,Rachel H. Roberts-Galbraith,Ning Yang,Tyler A. Zimmerman,Tyler A. Zimmerman,James J. Collins,James J. Collins,Ji Eun Lee,Ji Eun Lee,Neil L. Kelleher,Phillip A. Newmark,Jonathan V. Sweedler +12 more
TL;DR: The results suggest that even though the cephalic ganglia structure is visible after 6 days of regeneration, the original chemical composition of these regenerated structures is regained only after 12 days, and this prohormone is named SPP-20, and is up-regulated during regeneration in planarians.