James S. Wilkinson

Bio: James S. Wilkinson is an academic researcher from University of Southampton. The author has contributed to research in topics: Waveguide (optics) & Laser. The author has an hindex of 47, co-authored 321 publications receiving 7117 citations. Previous affiliations of James S. Wilkinson include University of Queensland & St Bartholomew's Hospital.

Optical fiber nanowires and microwires: fabrication and applications

Abstract: Microwires and nanowires have been manufactured by using a wide range of bottom-up techniques such as chemical or physical vapor deposition and top-down processes such as fiber drawing. Among these techniques, the manufacture of wires from optical fibers provides the longest, most uniform and robust nanowires. Critically, the small surface roughness and the high-homogeneity associated with optical fiber nanowires (OFNs) provide low optical loss and allow the use of nanowires for a wide range of new applications for communications, sensing, lasers, biology, and chemistry. OFNs offer a number of outstanding optical and mechanical properties, including (1) large evanescent fields, (2) high-nonlinearity, (3) strong confinement, and (4) low-loss interconnection to other optical fibers and fiberized components. OFNs are fabricated by adiabatically stretching optical fibers and thus preserve the original optical fiber dimensions at their input and output, allowing ready splicing to standard fibers. A review of the manufacture of OFNs is presented, with a particular emphasis on their applications. Three different groups of applications have been envisaged: (1) devices based on the strong confinement or nonlinearity, (2) applications exploiting the large evanescent field, and (3) devices involving the taper transition regions. The first group includes supercontinuum generators, a range of nonlinear optical devices, and optical trapping. The second group comprises knot, loop, and coil resonators and their applications, sensing and particle propulsion by optical pressure. Finally, mode filtering and mode conversion represent applications based on the taper transition regions. Among these groups of applications, devices exploiting the OFN-based resonators are possibly the most interesting; because of the large evanescent field, when OFNs are coiled onto themselves the mode propagating in the wire interferes with itself to give a resonator. In contrast with the majority of high-Q resonators manufactured by other means, the OFN microresonator does not have major issues with input-output coupling and presents a completely integrated fiberized solution. OFNs can be used to manufacture loop and coil resonators with Q factors that, although still far from the predicted value of 10. The input-output pigtails play a major role in shaping the resonator response and can be used to maximize the Q factor over a wide range of coupling parameters. Finally, temporal stability and robustness issues are discussed, and a solution to optical degradation issues is presented.

Waveguide surface plasmon resonance sensors

Abstract: Guided-wave optical biosensors have great potential for use in the field of environmental monitoring. In particular, planar waveguide technologies offer the possibility of producing compact, monolithic, multisensor devices which may be connected to instrumentation using optical fibres, allowing remote operation. Optical evanescent field sensing techniques presently under investigation include grating couplers, waveguide interferometers and surface plasmon resonance (SPR) sensors. In the latter case, the surface plasmon is generally excited using a "bulk" optical component such as a prism, and equipment using this technique is now commercially available. One potential advantage of the SPR technique is that the metal film which supports the surface plasmon may also be used as an electrode for electrochemical control of sensing reactions. However, recent reports have indicated that the "bulk" SPR devices may not ultimately be as sensitive as fully guided-wave approaches such as the Mach-Zehnder interferometer. An alternative to the "bulk" SPR devices which has recently emerged is the use of distributed coupling between a dielectric waveguide and the surface plasmon mode in a metal-coated waveguide. This has the advantage of combining greater design flexibility and the potential for monolithic integration with the well-established technique of SPR. However, at present no adequate model for the performance of these devices exists. ...

Integrated optical Mach-Zehnder biosensor

Abstract: We present measurements on biomolecular surface multilayers using an integrated optical sensor based on the Mach-Zehnder interferometer (MZI). The sensor design is unique in that it incorporates a three-waveguide coupler structure at the interferometer output which gives advantages in terms of signal referencing and in establishing and maintaining a sensitive operating point. The sensor performance is characterized with respect to bulk superstrate index and by the formation of multiple protein adlayers using a biotin-avidin-based biochemical system. The detection limit for protein loading is estimated as 5 pg/mm/sup 2/.

Metal nano-void photonic crystal for enhanced raman spectroscopy

Abstract: A planar optical platform for generating a Raman signal from a foreign object comprises an input region and an output region, for receiving and extracting optical radiation, optically coupled to a plasmonic band structure region. The plasmonic band structure region comprises a layer of a first material, having a first refractive index, patterned with an array of sub-regions of a second material, having a second refractive index, wherein a side-wall of each sub-region is coated with a metallodielectric layer. The array of sub-regions gives rise to a plasmonic band structure and, in use, each sub-region confines a plasmon resonance excited by optical radiation coupled into the plasmonic band structure region, which gives rise to a Raman signal from a foreign object placed proximate the plasmonic band structure region. The platform may be incorporated into a spectroscopic measurement system and is particularly useful for surface-enhanced Raman spectroscopy of analyte molecules.

Selective excitation of whispering gallery modes in a novel bottle microresonator

Abstract: Selective excitation of spheroidal whispering gallery modes and bottle modes in a robust bottle microresonator fabricated straightforwardly from a short section of optical fiber is demonstrated. Characteristic resonance spectra of long-cavity bottle modes were obtained by using a tapered fiber to excite evanescently bottle microresonator at different points along its axis. Compared to bare-fiber cylindrical resonators, the bottle microresonator results in a 35x increase of the observed Q factor.

Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology.

Abstract: Although gold is the subject of one of the most ancient themes of investigation in science, its renaissance now leads to an exponentially increasing number of publications, especially in the context of emerging nanoscience and nanotechnology with nanoparticles and self-assembled monolayers (SAMs). We will limit the present review to gold nanoparticles (AuNPs), also called gold colloids. AuNPs are the most stable metal nanoparticles, and they present fascinating aspects such as their assembly of multiple types involving materials science, the behavior of the individual particles, size-related electronic, magnetic and optical properties (quantum size effect), and their applications to catalysis and biology. Their promises are in these fields as well as in the bottom-up approach of nanotechnology, and they will be key materials and building block in the 21st century. Whereas the extraction of gold started in the 5th millennium B.C. near Varna (Bulgaria) and reached 10 tons per year in Egypt around 1200-1300 B.C. when the marvelous statue of Touthankamon was constructed, it is probable that “soluble” gold appeared around the 5th or 4th century B.C. in Egypt and China. In antiquity, materials were used in an ecological sense for both aesthetic and curative purposes. Colloidal gold was used to make ruby glass 293 Chem. Rev. 2004, 104, 293−346

Phd by thesis

Abstract: Deposits of clastic carbonate-dominated (calciclastic) sedimentary slope systems in the rock record have been identified mostly as linearly-consistent carbonate apron deposits, even though most ancient clastic carbonate slope deposits fit the submarine fan systems better. Calciclastic submarine fans are consequently rarely described and are poorly understood. Subsequently, very little is known especially in mud-dominated calciclastic submarine fan systems. Presented in this study are a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) that reveals a >250 m thick calciturbidite complex deposited in a calciclastic submarine fan setting. Seven facies are recognised from core and thin section characterisation and are grouped into three carbonate turbidite sequences. They include: 1) Calciturbidites, comprising mostly of highto low-density, wavy-laminated bioclast-rich facies; 2) low-density densite mudstones which are characterised by planar laminated and unlaminated muddominated facies; and 3) Calcidebrites which are muddy or hyper-concentrated debrisflow deposits occurring as poorly-sorted, chaotic, mud-supported floatstones. These

Surface plasmon resonance sensors: review

Abstract: Since the first application of the surface plasmon resonance (SPR) phenomenon for sensing almost two decades ago, this method has made great strides both in terms of instrumentation development and applications. SPR sensor technology has been commercialized and SPR biosensors have become a central tool for characterizing and quantifying biomolecular interactions. This paper attempts to review the major developments in SPR technology. Main application areas are outlined and examples of applications of SPR sensor technology are presented. Future prospects of SPR sensor technology are discussed.

Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species

Abstract: 5.1. Detection Formats 475 5.2. Food Quality and Safety Analysis 477 5.2.1. Pathogens 477 5.2.2. Toxins 479 5.2.3. Veterinary Drugs 479 5.2.4. Vitamins 480 5.2.5. Hormones 480 5.2.6. Diagnostic Antibodies 480 5.2.7. Allergens 481 5.2.8. Proteins 481 5.2.9. Chemical Contaminants 481 5.3. Medical Diagnostics 481 5.3.1. Cancer Markers 481 5.3.2. Antibodies against Viral Pathogens 482 5.3.3. Drugs and Drug-Induced Antibodies 483 5.3.4. Hormones 483 5.3.5. Allergy Markers 483 5.3.6. Heart Attack Markers 484 5.3.7. Other Molecular Biomarkers 484 5.4. Environmental Monitoring 484 5.4.1. Pesticides 484 5.4.2. 2,4,6-Trinitrotoluene (TNT) 485 5.4.3. Aromatic Hydrocarbons 485 5.4.4. Heavy Metals 485 5.4.5. Phenols 485 5.4.6. Polychlorinated Biphenyls 487 5.4.7. Dioxins 487 5.5. Summary 488 6. Conclusions 489 7. Abbreviations 489 8. Acknowledgment 489 9. References 489