J
Jan Ježek
Researcher at Rowan University
Publications - 2
Citations - 343
Jan Ježek is an academic researcher from Rowan University. The author has contributed to research in topics: Cyclin-dependent kinase 8 & Cyclin. The author has an hindex of 2, co-authored 2 publications receiving 234 citations.
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Journal ArticleDOI
Reactive Oxygen Species and Mitochondrial Dynamics: The Yin and Yang of Mitochondrial Dysfunction and Cancer Progression
TL;DR: The latest findings on the intricate relationship between mitochondrial dynamics and ROS production are reviewed, focusing mainly on its role in malignant disease.
Journal ArticleDOI
Cyclin C: The Story of a Non-Cycling Cyclin
Jan Ježek,Daniel G.J. Smethurst,David C. Stieg,Z. A. C. Kiss,Sara E. Hanley,Vidyaramanan Ganesan,Kai-Ti Chang,Katrina F. Cooper,Randy Strich +8 more
TL;DR: Cyclin C-induced mitochondrial fission was found to increase sensitivity of both mammalian and yeast cells to apoptosis, and its transcriptional and non-transcriptional roles in tumor promotion or suppression are reviewed.