Showing papers by "Janet B. W. Williams published in 2016"

SCID-5-CV : structured clinical interview for DSM-5 disorders : clinician version

Abstract: The Structured Clinical Interview for DSM-5(R) -- Clinician Version (SCID-5-CV) guides the clinician step-by-step through the DSM-5 diagnostic process. Interview questions are provided conveniently along each corresponding DSM-5 criterion, which aids in rating each as either present or absent. The SCID-5-CV is an abridged and reformatted version of the Research Version of the SCID, the structured diagnostic interview most widely used by researchers for making DSM diagnoses for the past 30 years. A unique and valuable tool, the SCID-5-CV covers the DSM-5 diagnoses most commonly seen in clinical settings: depressive and bipolar disorders; schizophrenia spectrum and other psychotic disorders; substance use disorders; anxiety disorders (panic disorder, agoraphobia, social anxiety disorder, generalized anxiety disorder); obsessive-compulsive disorder; posttraumatic stress disorder; attention-deficit/hyperactivity disorder; and adjustment disorder. It also screens for 17 additional DSM-5 disorders. Versatile in function, the SCID-5-CV can be used in a variety of ways. For example, it can ensure that all of the major DSM-5 diagnoses are systematically evaluated in adults; characterize a study population in terms of current psychiatric diagnoses; and improve interviewing skills of students in the mental health professions, including psychiatry, psychology, psychiatric social work, and psychiatric nursing. Enhancing the reliability and validity of DSM-5 diagnostic assessments, the SCID-5-CV will serve as an indispensible interview guide.

User's guide for the SCID-5-CV : structured clinical interview for DSM-5 disorders : clinician version

Abstract: The Structured Clinical Interview for DSM-5 Disorders -- Clinician Version (SCID-5-CV) guides the clinician step-by-step through the DSM-5 diagnostic process. Interview questions are provided conveniently along each corresponding DSM-5 criterion, which aids in rating each as either present or absent. A unique and valuable tool, the SCID-5-CV covers the DSM-5 diagnoses most commonly seen in clinical settings. The User's Guide for the SCID-5-CV provides comprehensive instructions on how to use the SCID-5-CV effectively and accurately. It not only describes the rationale, structure, conventions, and usage of the SCID-5-CV, but also discusses in detail how to interpret and apply the specific DSM-5 criteria for each of the disorders included in the SCID-5-CV. A number of sample role-play and homework cases are also included to help clinicians learn how to use the SCID-5-CV. Together with the SCID-5-CV, the User's Guide for the SCID-5-CV will prove invaluable to clinicians, researchers, interviewers, and students in the mental health professions who seek to integrate time-tested interview questions corresponding to the DSM-5 criteria into their DSM-5 diagnostic assessment process.

User's guide for the SCID-5-PD : structured clinical interview for DSM-5 personality disorders

Abstract: Acknowledgments, Citation and Additional Copyright Notices, Disclosures, 1. Introduction, 2. History, 3. Features of the SCID-5-PD, 3.1 Coverage, 3.2 Diagnostic Summary Score Sheet, 3.3 Basic Structure, 3.4 Screening Personality Questionnaire (SCID-5-SPQ), 3.5 Deviations From DSM-5 Criteria, 4. Administration of the SCID-5-PD, 4.1 Sources of Information, 4.2 SCID-5-PD Interview Questions, 4.3 Interview Questions With Parenthetical Words in All-Capital Letters, 4.4 Ratings of Criterion Items, 4.5 Assessment of Other Specified Personality Disorder, 4.6 Use of the SCID-5-PD With the SCID-5-SPQ, 4.7 Use of the SCID-5-PD Without the SCID-5-SPQ, 5. SCID-5-PD Item-by-Item Commentary, 5.1 Avoidant Personality Disorder, 5.2 Dependent Personality Disorder, 5.3 Obsessive-Compulsive Personality Disorder, 5.4 Paranoid Personality Disorder, 5.5 Schizotypal Personality Disorder, 5.6 Schizoid Personality Disorder, 5.7 Histrionic Personality Disorder, 5.8 Narcissistic Personality Disorder, 5.9 Borderline Personality Disorder, 5.10 Antisocial Personality Disorder, 6. Training, 7. Reliability and Validity, 7.1 Reliability of the SCID-5-PD, 7.2 Validity of the SCID-II, 7.3 Psychometric Properties of the SCID-II Patient Questionnaire, References, Appendix: SCID-5-SPQ and SCID-5-PD Example

The Depression Inventory Development Workgroup: A Collaborative, Empirically Driven Initiative to Develop a New Assessment Tool for Major Depressive Disorder.

Abstract: The Depression Inventory Development project is an initiative of the International Society for CNS Drug Development whose goal is to develop a comprehensive and psychometrically sound measurement tool to be utilized as a primary endpoint in clinical trials for major depressive disorder. Using an iterative process between field testing and psychometric analysis and drawing upon expertise of international researchers in depression, the Depression Inventory Development team has established an empirically driven and collaborative protocol for the creation of items to assess symptoms in major depressive disorder. Depression-relevant symptom clusters were identified based on expert clinical and patient input. In addition, as an aid for symptom identification and item construction, the psychometric properties of existing clinical scales (assessing depression and related indications) were evaluated using blinded datasets from pharmaceutical antidepressant drug trials. A series of field tests in patients with major depressive disorder provided the team with data to inform the iterative process of scale development. We report here an overview of the Depression Inventory Development initiative, including results of the third iteration of items assessing symptoms related to anhedonia, cognition, fatigue, general malaise, motivation, anxiety, negative thinking, pain and appetite. The strategies adopted from the Depression Inventory Development program, as an empirically driven and collaborative process for scale development, have provided the foundation to develop and validate measurement tools in other therapeutic areas as well.

Identifying Patients With Depression in the Primary Care Setting

Abstract: OBJECTIVE To determine if there is a core subset of depressive symptoms that could be used to efficiently diagnose depression after administering the 2-item PRIME-MD a screening questionnaire for depression. METHODS One thousand patients selected randomly and by convenience from 4 primary care clinics were assessed by PRIME-MD and completed a questionnaire measuring the following validation variables: functional status and well-being, disability days, somatic symptoms, depression severity, suicidal thoughts, health care utilization, and the physician-patient relationship. RESULTS Four symptoms (sleep disturbance, anhedonia, low self-esteem, and decreased appetite) accounted for virtually all the depression symptom-related variance in functional status and well-being, with 8.3% of patients having 2 of these symptoms and 8.2% having 3 or 4 of these symptoms. There was excellent agreement between diagnosis based on core symptoms and major depression (K= 0.77; overall accuracy rate, 94%). There were significant differences (P<.001) among patients with negative depression screen, 0 to 1, 2, and 3 to 4 core symptoms with scores on each of the validation variables getting progressively worse in these 4 groups. A cutoff point of 2 core symptoms identified all but 3 patients with major depression and an additional 5% of the entire sample without major depression who were significantly (P<.05) worse than patients without depression on each of the validation variables. CONCLUSION A strategy that includes the use of a 2-item depression screener followed by the evaluation of 4 core depressive symptoms is an efficient and effective way of identifying and classifying primary care patients with depression in need of clinical attention.