J
Janine Woehlk
Researcher at University of Chicago
Publications - 1
Citations - 29
Janine Woehlk is an academic researcher from University of Chicago. The author has contributed to research in topics: Wnt signaling pathway & Inflammation. The author has an hindex of 1, co-authored 1 publications receiving 8 citations.
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Wnt-β-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression.
Jasmin Quandt,Stephen Arnovitz,Leila Haghi,Janine Woehlk,Azam Mohsin,Michael K. Okoreeh,Priya S. Mathur,Akinola Olumide Emmanuel,Abu Osman,Manisha Krishnan,Samuel B. Morin,Alexander T. Pearson,Randy F. Sweis,Joel Pekow,Christopher R. Weber,Khashayarsha Khazaie,Fotini Gounari +16 more
TL;DR: In this paper, Wnt-β-catenin activation induced newly accessible chromatin sites in these genes and upregulated their expression, leading to a disease-associated increase in the frequency of RORγt+ Treg cells coexpressing multiple pro-inflammatory cytokines.