J
Janneke P. Ouwerkerk
Researcher at Wageningen University and Research Centre
Publications - 11
Citations - 3906
Janneke P. Ouwerkerk is an academic researcher from Wageningen University and Research Centre. The author has contributed to research in topics: Akkermansia muciniphila & Biology. The author has an hindex of 7, co-authored 9 publications receiving 2889 citations.
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Journal ArticleDOI
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
Amandine Everard,Clara Belzer,Lucie Geurts,Janneke P. Ouwerkerk,Céline Druart,Laure B. Bindels,Yves Guiot,Muriel Derrien,Giulio G. Muccioli,Nathalie M. Delzenne,Willem M. de Vos,Willem M. de Vos,Patrice D. Cani +12 more
TL;DR: Substantial insight is provided into the intricate mechanisms of bacterial regulation of the cross-talk between the host and gut microbiota and provides a rationale for the development of a treatment that uses this human mucus colonizer for the prevention or treatment of obesity and its associated metabolic disorders.
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Akkermansia muciniphila induces gut microbiota remodelling and controls islet autoimmunity in NOD mice
Arno Hänninen,Arno Hänninen,Raine Toivonen,Sakari Pöysti,Clara Belzer,Hubert Plovier,Janneke P. Ouwerkerk,Rohini Emani,Patrice D. Cani,Willem M. de Vos +9 more
TL;DR: Transfer of the whole microbiota may not reduceabetes incidence despite a major change in gut microbiota, but single symbionts such as A. muciniphila with beneficial metabolic and immune signalling effects may reduce diabetes incidence when administered as a probiotic.
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Glycobiome: bacteria and mucus at the epithelial interface.
TL;DR: This review is focussed on the host-microbe interactions within the glycan landscape at the epithelial interface and considers the spatial organisation and composition of the mucosa-associated microbiota in health and disease.
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Adaptation of Akkermansia muciniphila to the oxic-anoxic interface of the mucus layer
Janneke P. Ouwerkerk,Kees C. H. van der Ark,Mark Davids,Nico J. Claassens,Teresa Robert Finestra,Willem M. de Vos,Willem M. de Vos,Clara Belzer +7 more
TL;DR: It is concluded that A. muciniphila can use oxygen when it is present at nanomolar concentrations, which has direct relevance for applicability, as addition of low oxygen concentrations could benefit the in vitro growth of certain anaerobic organisms.
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Akkermansia Glycaniphila Sp. Nov., an Anaerobic Mucin-Degrading Bacterium Isolated From Reticulated Python Faeces
TL;DR: Based on phenotypic, phylogenetic and genetic characteristics, strain PytT represents a novel species of the genus Akkermansia, for which the name Akker mansia glycaniphila sp.