J
Jason S. Papadopoulos
Researcher at National Institutes of Health
Publications - 3
Citations - 14215
Jason S. Papadopoulos is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Conserved Domain Database & Simple Modular Architecture Research Tool. The author has an hindex of 3, co-authored 3 publications receiving 10613 citations.
Papers
More filters
Journal ArticleDOI
BLAST+: architecture and applications.
Christiam Camacho,George Coulouris,Vahram Avagyan,Ning Ma,Jason S. Papadopoulos,Kevin Bealer,Thomas L. Madden +6 more
TL;DR: The new BLAST command-line applications, compared to the current BLAST tools, demonstrate substantial speed improvements for long queries as well as chromosome length database sequences.
Journal ArticleDOI
COBALT: constraint-based alignment tool for multiple protein sequences
TL;DR: It is shown that using constraints derived from the conserved domain database (CDD) and PROSITE protein-motif database improves COBALT's alignment quality and has reasonable runtime performance and alignment accuracy comparable to or exceeding that of other tools for a broad range of problems.
Journal ArticleDOI
Improved BLAST searches using longer words for protein seeding
TL;DR: An improved trade-off between running time and retrieval accuracy is demonstrated, controlled by the score threshold used for short word matches, while achieving ROC scores similar to those obtained with current default parameters.