Javier Palazon

TL;DR: An overview of the chemical structures of triterpenoid components and their biological activity is presented, focusing on two novel activities, tumor inhibition and antiangiogenic properties of withaferin A and the effects of withanolide A on Alzheimer's disease.

TL;DR: The enhancing effects of elicitors on the production of high-added value plant compounds such as taxanes, ginsenosides, aryltetralin lignans and other types of polyphenols are summarized, focusing particularly on the use of a new generation of elicitor such as coronatine and cyclodextrins.

TL;DR: Recent advances in the production of taxol and related taxanes in Taxus baccata, the taxol-producing European yew, using cell suspension culture technology are focused on, giving particular emphasis to the optimization steps that have improved production and including the most recently developed new tools.

TL;DR: In vitro and in vivo studies have shown that amyrin also has important biological functions, and the compounds commonly found in medicinal plants and oleo-resin obtained by bark incision of several species of Bursera or Protium of the Burseraceae family.

TL;DR: Current research in the design of new taxol-related compounds, the chemical structure/anti-cancer activity relationship and new formulations of the drug are discussed, as are the optimizing strategies to improve taxol and related taxoid production in cell cultures, as well as the current knowledge of taxol metabolism.