J
Javier Salmerón
Researcher at Carlos III Health Institute
Publications - 84
Citations - 3967
Javier Salmerón is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Hepatitis C & Hepatitis C virus. The author has an hindex of 24, co-authored 79 publications receiving 3559 citations. Previous affiliations of Javier Salmerón include University of Granada.
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Journal ArticleDOI
Drug-Induced Liver Injury: An Analysis of 461 Incidences Submitted to the Spanish Registry Over a 10-Year Period
Raúl J. Andrade,M. Isabel Lucena,M. Carmen Fernández,G. Pelaez,Ketevan Pachkoria,Elena García-Ruiz,B. García-Muñoz,Rocío González-Grande,Angeles Pizarro,José Antonio Durán,Manuel Jimenez,Luis Rodrigo,Manuel Romero-Gómez,J.M. Navarro,Ramon Planas,Joan Costa,Africa Borras,Aina Soler,Javier Salmerón,Rafael Martín-Vivaldi +19 more
TL;DR: Patients with drug-induced hepatocellular jaundice have 11.7% chance of progressing to death or transplantation, and amoxicillin-clavulanate stands out as the most common drug related to DILI.
Journal ArticleDOI
Outcome of acute idiosyncratic drug‐induced liver injury: Long‐term follow‐up in a hepatotoxicity registry
Raúl J. Andrade,M. Isabel Lucena,Neil Kaplowitz,Beatriz García‐Muņoz,Y. Borraz,Ketevan Pachkoria,Miren García-Cortés,M. Carmen Fernández,G. Pelaez,Luis Rodrigo,José Antonio Durán,Joan Costa,Ramon Planas,A.M. Barriocanal,Carlos Guarner,Manuel Romero-Gómez,Teresa Muņoz‐Yagüe,Javier Salmerón,Ramón Hidalgo +18 more
TL;DR: Patients with cholestatic/mixed injury were more prone to chronicity than patients with hepatocellular injury, and cardiovascular and central nervous system drugs are the main groups leading to chronic liver damage.
Journal ArticleDOI
Phenotypic characterization of idiosyncratic drug‐induced liver injury: The influence of age and sex
M. Isabel Lucena,Raúl J. Andrade,Neil Kaplowitz,Miren García-Cortés,M. Carmen Fernández,Manuel Romero-Gómez,Miguel Bruguera,H. Hallal,Mercedes Robles-Díaz,Jose F. Rodriguez‐González,J.M. Navarro,Javier Salmerón,Pedro Martinez‐Odriozola,Ramón Pérez-Álvarez,Y. Borraz,Ramón Hidalgo +15 more
TL;DR: Neither older age nor female sex are predisposing factors to overall DILI, however, older age is a determinant for cholestatic damage with a male predominance, whereas younger age is associated with cytolytic damage and a female overrepresentation.
Journal ArticleDOI
HIV coinfection shortens the survival of patients with hepatitis C virus‐related decompensated cirrhosis
Juan A. Pineda,Manuel Romero-Gómez,Fernando Díaz-García,José A. Girón-González,José Luis Montero,Julián Torre-Cisneros,Raúl J. Andrade,Mercedes González-Serrano,José Aguilar,Manuela Aguilar-Guisado,J.M. Navarro,Javier Salmerón,Francisco J. Caballero-Granado,José A. García-García +13 more
TL;DR: HIV coinfection reduces considerably the survival of patients with HCV‐related ESLD independently of other markers of poor prognosis, including age and the type of the first hepatic decompensation.
Journal ArticleDOI
Increased Risk of Autoimmune Thyroid Disease in Hepatitis C vs Hepatitis B Before, During, and After Discontinuing Interferon Therapy
Luisa Fernandez-Soto,Amalia Gonzalez,Fernando Escobar-Jiménez,Rafael Vazquez,Esther Ocete,Nicolás Olea,Javier Salmerón +6 more
TL;DR: Systematic screening of thyroid gland function and TPOAb titers in all patients with HCV before, during, and after IFN-alpha therapy appears warranted, and patients withHCV are more susceptible than patients with HBV to autoimmune thyroid disease.