Jaw-Chyun Chen

TL;DR: Emodin, an anthraquinone compound derived from genus Rheum and Polygonum, significantly blocked the S protein and ACE2 interaction in a dose-dependent manner and suggested that emodin may be considered as a potential lead therapeutic agent in the treatment of SARS.

TL;DR: Berberine, the protoberberine alkaloid widely distributed in the plant kingdom, was capable of suppressing inflammatory agents-induced cytokine production in lung cells and suggested the potential role of berberine in the treatment of pulmonary inflammation.

TL;DR: It is demonstrated that ginger significantly blocked the binding of LT to cell-surface receptor G M1, resulting in the inhibition of fluid accumulation in the closed ileal loops of mice, providing evidence that ginger and its derivatives may be effective herbal supplements for the clinical treatment of enterotoxigenic Escherichia coli diarrhea.

TL;DR: Vanillin is identified as an anti-inflammatory compound with the capacity to prevent and ameliorate TNBS-induced colitis and could be a potent candidate for the treatment of IBD.

TL;DR: SP-10 blocked both binding of the S protein and infectivity of S protein-pseudotyped retrovirus to Vero E6 cells, the first report of small peptides designed to disrupt the binding of SARS-CoV S protein to ACE2.