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Jayashree Acharya

Bio: Jayashree Acharya is an academic researcher from University of Calcutta. The author has contributed to research in topics: Pedicel & Sugar. The author has an hindex of 4, co-authored 6 publications receiving 48 citations. Previous affiliations of Jayashree Acharya include Indian Institute of Technology Kharagpur.

Papers
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Journal ArticleDOI
TL;DR: In this article, the essential oils were extracted from seven local varieties of P. betle L. leaves (Bangla, Bagerhati, Manikdanga, Meetha, Kalibangla, Chhaanchi and Ghanagete) with the aim to characterize the varieties on the basis of oil constituents and to study their enzyme inhibitory and cytotoxic properties.

31 citations

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TL;DR: The activities of the flower extracts against the enzymes suggest that they may have beneficial effects in controlling diseases, and the chemical constituents present in the methanol extracts were profiled following GC-MS based metabolomics approach.
Abstract: The flower extracts of two cultivated varieties of Musa X paradisiaca viz. Kanthali and Kancha Kela were assayed against the enzymes α-amylase, α-glucosidase, acetylcholinesterase, β-glucuronidase and Angiotensin I Converting Enzyme, which are related to different diseased states like diabetes, Alzheimer's disease, hepatic disorder and cardiovascular diseases, respectively. The extracts inhibited all the enzymes except α-amylase by Musa X paradisiaca cv. Kanthali. Significantly high activities were observed in both the cultivated varieties for inhibiting the enzymes β-glucuronidase and Angiotensin I Converting Enzyme with respect to the known inhibitors of such enzymes silymarin and Lisinopril, respectively. The chemical constituents present in the methanol extracts were profiled following GC-MS based metabolomics approach. Eleven organic acids, seven sugars and sugar alcohols, six fatty acids, three phenols, two amino acids and a sterol could be identified. Practical Applications The male flowers of Musa X paradisiaca are cooked as vegetable in South-East Asia. The flowers are also useful in diabetes. Enzyme inhibitors have properties to prevent or control different noninfectious diseases. So, the flower extracts of two varieties of the plant were assayed for their activities against the glycosidases, acetylcholinesterase, β-glucuronidase and Angiotensin I Converting Enzyme. The activities of the flower extracts against the enzymes suggest that they may have beneficial effects in controlling diseases.

17 citations

Journal ArticleDOI
TL;DR: It is suggested that the metabolites present in the fruit mesocarp tissue showed the potential antioxidant activity and properties to inhibit the enzymes α-amylase and α-glucosidase.
Abstract: Phoenix sylvestris is an underutilized seasonal fruit in West Bengal, India. Methanol extract and extracts after alkaline hydrolysis of the mesocarp tissue of full-mature edible fruits of P. sylvestris were analyzed by GC-MS following a metabolomics approach. The fractions were tested for their antioxidant and inhibitory properties against the two key enzymes involved in diabetes, α-amylase, and α-glucosidase. Total 71 metabolites belonging to organic acids, amino acids, sugars, sugar alcohols, fatty acids, and phenols were identified in the methanol extract and in fractions after saponification. All the extracts and fractions showed high antioxidant, α-glucosidase, and α-amylase inhibitory activities. Sugars like raffinose (IC50 = 0.36 μM), sucrose (IC50 = 0.51 μM), trehalose (IC50 = 0.85 μM), and phenols like taxifolin (IC50 = 0.31 μM), benzoic acid (IC50 = 2.74 μM) inhibited only the enzyme α-amylase. Phenolic components which inhibited both the enzymes were caffeic acid (IC50 = 1.42 μM for α-a...

10 citations

Journal ArticleDOI
TL;DR: Multivariate analysis carried out revealed that sesquiterpenes and a few monoterpenes played important role to distinguish species particularly C. longa.

6 citations


Cited by
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Journal ArticleDOI
TL;DR: The current literature on plant-derived ACE-inhibitory peptides including their sources, production and structure, as well as their activity by in vitro and in vivo studies and their bioavailability are reviewed.
Abstract: Hypertension is an important factor in cardiovascular diseases. Angiotensin-I-converting enzyme (ACE) inhibitors like synthetic drugs are widely used to control hypertension. ACE-inhibitory peptides from food origins could be a good alternative to synthetic drugs. A number of plant-based peptides have been investigated for their potential ACE inhibitor activities by using in vitro and in vivo assays. These plant-based peptides can be obtained by solvent extraction, enzymatic hydrolysis with or without novel food processing methods, and fermentation. ACE-inhibitory activities of peptides can be affected by their structural characteristics such as chain length, composition and sequence. ACE-inhibitory peptides should have gastrointestinal stability and reach the cardiovascular system to show their bioactivity. This paper reviews the current literature on plant-derived ACE-inhibitory peptides including their sources, production and structure, as well as their activity by in vitro and in vivo studies and their bioavailability.

193 citations

Journal ArticleDOI
TL;DR: A compendium of exploits in the present millennium directed towards the inhibition of β GLU is presented, to proffer a platform on which new scaffolds can be modelled for improved βGLU inhibitory potency and the development of new therapeutic agents in consequential.

66 citations

Journal ArticleDOI
TL;DR: Recent advances in untargeted/targeted fingerprinting approaches were described and their application in the taxonomic identification, classification and authentication of plants (medicinal) and essential oils discussed.

62 citations

Journal ArticleDOI
TL;DR: The aim of this review is to provide new findings on health effects of edible flowers since 2015, and some newly found phytochemicals such as polysaccharides were shown to be beneficial to human health.

48 citations

Journal ArticleDOI
TL;DR: The present review provides information on extraction techniques, identification of bioactive compounds, and their biological activities, and information on processing, preservation, and health benefits along with their mechanisms has been added.
Abstract: Piper betle L., belonging to Piperaceae family, known as a traditional herbal medicinal plant and used for several health benefits in Asian countries. Currently, demand for its products such as herbal drugs, medicines, and natural herbal formulations has increased. The beneficial effects of betel leaves and its products have traditionally exploited for the treatment of several diseases like bad breath, cuts, injuries, inflammations, cold cough, indigestion, etc. Till now, a broad range of bioactive compounds including polyphenols, terpenes, etc., has been identified from the extracts and essential oil (EO) of betel leaves. The structural and functional characterization of the extract and EO bio-actives has been derived by various advanced standard methods. Most of the health-related benefits of betel leaves have been associated with their bioactive phenolic compounds. The extract of this highly perishable product can be used in organic synthesis, food, and beverage industry, pharmaceuticals, etc., to the environmental issues. The present review provides information on extraction techniques, identification of bioactive compounds, and their biological activities. That apart, information on processing, preservation, and health benefits along with their mechanisms has also been added.

45 citations