Jayasree Seayad

Bio: Jayasree Seayad is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Catalysis & Amination. The author has an hindex of 18, co-authored 43 publications receiving 2630 citations. Previous affiliations of Jayasree Seayad include International Council for the Exploration of the Sea & University of Rostock.

Catalytic Markovnikov and anti-Markovnikov functionalization of alkenes and alkynes: recent developments and trends.

Abstract: The regioselective functionalization of terminal alkenes and alkynes is of utmost importance for the synthesis of a wide variety of organic products. Based on the original observation by Vladimir Markovnikov-the pioneer of this field of research-in the 19th century, the possible regioisomeric products are classified as Markovnikov or anti-Markovnikov products. Contrary to traditional belief, it is nowadays possible to control the regiochemistry of various additions of nucleophiles to alkenes and alkynes by applying different transition-metal catalysts. Recent developments in this area of selective functionalization of alkenes and alkynes are reviewed.

Catalytic Asymmetric Pictet−Spengler Reaction

Abstract: A catalytic asymmetric Pictet−Spengler reaction has been developed, wherein treating substituted tryptamines with an aldehyde in the presence of a catalytic amount of a chiral phosphoric acid provides the corresponding tetrahydro-β-carboline derivatives in high yields and enantiomeric excesses. The reaction works well with both aliphatic and aromatic aldehydes.

Base-Catalyzed Hydroamination of Olefins: An Environmentally Friendly Route to Amines

Abstract: The base-catalyzed hydroamination of olefins offers a simple and elegant access to various primary, secondary, and tertiary amines. Particular focus is placed on developments in the area of hydroamination of non-activated olefins. Advantages and disadvantages of the methodology compared to other synthetic methods are presented. Special attention is paid to potential industrial applications of this chemistry.

Katalytische Markownikow‐ und Anti‐Markownikow‐Funktionalisierung von Alkenen und Alkinen

Abstract: Reaktionen zur selektiven Veredelung von Alkenen zahlen zu den wichtigsten Methoden in der Organischen Synthese. Durch die Entwicklung von Ubergangsmetallkatalysatoren in den letzten Jahrzehnten konnen heute alle Arten von Selektivitat bei einer Vielzahl von Transformationen effizient gesteuert werden. Auch 100 Jahre nach dem Tod von Vladimir Markownikow – dem Pionier auf diesem Gebiet – ist die regioselektive Funktionalisierung von Alkenen und Alkinen immer noch ein wichtiges Forschungsziel: Besonders die Anti-Markownikow-Addition von Sauerstoff- und Stickstoff-Nucleophilen an aliphatische Alkene und Alkine verfugt uber groses industrielles Potenzial. In diesem Aufsatz werden neuere Entwicklungen auf diesem Gebiet beschrieben. Eine Auswahl aktueller Beispiele zeigt, wie die Regioselektivitat durch die Wahl des Katalysators gesteuert werden kann.

Advances and adventures in amination reactions of olefins and alkynes

Abstract: Recent developments in the area of transition metal-catalyzed amination of olefins and alkynes are reviewed. Special emphasis is given to rhodium-catalyzed oxidative aminations of aromatic olefins.

Hydroamination: direct addition of amines to alkenes and alkynes.

Abstract: 8.4.5. Nitromercuration Reactions 3878 9. Hydroamination of Alkenes and Alkynes under Microwave Irradiation 3878 * To whom correspondence should be addressed. Phone: +49 241 8

3d Transition Metals for C-H Activation.

Abstract: C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with notable applications to material sciences, crop protection, drug discovery, and pharmaceutical industries, among others. Despite major advances, the vast majority of these C–H functionalizations required precious 4d or 5d transition metal catalysts. Given the cost-effective and sustainable nature of earth-abundant first row transition metals, the development of less toxic, inexpensive 3d metal catalysts for C–H activation has gained considerable recent momentum as a significantly more environmentally-benign and economically-attractive alternative. Herein, we provide a comprehensive overview on first row transition metal catalysts for C–H activation until summer 2018.