Jean-Baptiste Sortais

Bio: Jean-Baptiste Sortais is an academic researcher from Institut Universitaire de France. The author has contributed to research in topics: Catalysis & Hydrosilylation. The author has an hindex of 40, co-authored 116 publications receiving 4278 citations. Previous affiliations of Jean-Baptiste Sortais include İnönü University & University of Toulouse.

Efficient and selective N-alkylation of amines with alcohols catalysed by manganese pincer complexes.

Abstract: Borrowing hydrogen (or hydrogen autotransfer) reactions represent straightforward and sustainable C-N bond-forming processes. In general, precious metal-based catalysts are employed for this effective transformation. In recent years, the use of earth abundant and cheap non-noble metal catalysts for this process attracted considerable attention in the scientific community. Here we show that the selective N-alkylation of amines with alcohols can be catalysed by defined PNP manganese pincer complexes. A variety of substituted anilines are monoalkylated with different (hetero)aromatic and aliphatic alcohols even in the presence of other sensitive reducible functional groups. As a special highlight, we report the chemoselective monomethylation of primary amines using methanol under mild conditions.

Iron‐Catalyzed α‐Alkylation of Ketones with Alcohols

Abstract: A general and benign iron-catalyzed α-alkylation reaction of ketones with primary alcohols has been developed. The key to success of the reaction is the use of a Knolker-type complex as catalyst (2 mol %) in the presence of Cs2 CO3 as base (10 mol %) under hydrogen-borrowing conditions. Using 2-aminobenzyl alcohol as alkylation reagent allows for the "green" synthesis of quinoline derivatives.

Cycloruthenated Compounds – Synthesis and Applications

Abstract: The syntheses of cycloruthenated compounds by several methods, and especially by the C–H activation pathway, have been reviewed. Many ruthenium-containing starting materials lead to these interesting organometallic compounds, which have found various applications in different fields of chemistry. Their reactivity highlights both thevariety of reactions that were found to occur at the Ru–C bonds as well as the inertness of the organometallic moiety when these species are exposed to strongly oxidizing molecules or to reactive halogenation reagents. Their use as catalyst precursors showed them to be particularly efficient for hydrogenation reactions, either by H2 or by hydride transfer. Physicochemical characteristics of cycloruthenated complexes include: (i) a cathodic shift of the electrochemical potentials corresponding to various redox couples, (ii) a bathochromic shift of UV/Vis absorption bands, (iii) valuable luminescence properties. Dinuclear cycloruthenated complexes display specific properties connected to interactions between the metals, such as strong electronic coupling, evidenced by intervalence bands of mixed-valence species, or efficient energy transfer.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

N‐Heterocyclic Carbene Ligands and Iron: An Effective Association for Catalysis

Abstract: Although iron has been known and widely used in coordination and organometallic chemistry for decades and N-heterocyclic carbenes (NHCs) have also been used for about half a century, their combination surprisingly did not become a hot topic in chemistry until this last decade. This review presents several recent and stimulating developments in homogeneous catalysis done mainly using iron/NHC-based catalysts. Of particular interest are the roles of iron/NHC complexes in cross-coupling Kochi reactions, CC bond formation reactions and hydrofunctionalization, and more particularly in hydrosilylation. Our review summarizes the key developments in these fields.

An overview of N-heterocyclic carbenes

Abstract: The successful isolation and characterization of an N-heterocyclic carbene in 1991 opened up a new class of organic compounds for investigation. From these beginnings as academic curiosities, N-heterocyclic carbenes today rank among the most powerful tools in organic chemistry, with numerous applications in commercially important processes. Here we provide a concise overview of N-heterocyclic carbenes in modern chemistry, summarizing their general properties and uses and highlighting how these features are being exploited in a selection of pioneering recent studies.

3d Transition Metals for C-H Activation.

Abstract: C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with notable applications to material sciences, crop protection, drug discovery, and pharmaceutical industries, among others. Despite major advances, the vast majority of these C–H functionalizations required precious 4d or 5d transition metal catalysts. Given the cost-effective and sustainable nature of earth-abundant first row transition metals, the development of less toxic, inexpensive 3d metal catalysts for C–H activation has gained considerable recent momentum as a significantly more environmentally-benign and economically-attractive alternative. Herein, we provide a comprehensive overview on first row transition metal catalysts for C–H activation until summer 2018.