J
Jean-Charles Sanchez
Researcher at University of Geneva
Publications - 311
Citations - 28689
Jean-Charles Sanchez is an academic researcher from University of Geneva. The author has contributed to research in topics: Proteome & Proteomics. The author has an hindex of 72, co-authored 303 publications receiving 25148 citations. Previous affiliations of Jean-Charles Sanchez include Geneva College & University of Basel.
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pROC: an open-source package for R and S+ to analyze and compare ROC curves
Xavier Robin,Natacha Turck,Alexandre Hainard,Natalia Tiberti,Frédérique Lisacek,Jean-Charles Sanchez,Markus Müller +6 more
TL;DR: pROC as mentioned in this paper is a package for R and S+ that contains a set of tools displaying, analyzing, smoothing and comparing ROC curves in a user-friendly, object-oriented and flexible interface.
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Progress with Proteome Projects: Why all Proteins Expressed by a Genome Should be Identified and How To Do It
Marc R. Wilkins,Jean-Charles Sanchez,Andrew A. Gooley,Ron D. Appel,Ian Humphery-Smith,Denis F. Hochstrasser,Keith L. Williams +6 more
TL;DR: The Progress with Proteome Projects: Why all Proteins Expressed by a Genome Should be Identified and How To Do It as discussed by the authors is an example of such a project.
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The focusing positions of polypeptides in immobilized pH gradients can be predicted from their amino acid sequences
Bengt Bjellqvist,Graham J. Hughes,Christian Pasquali,Nicole Paquet,Florence Ravier,Jean-Charles Sanchez,Séverine Frutiger,Denis F. Hochstrasser +7 more
TL;DR: The advantages of being able to predict the position of a protein of known structure within a two‐dimensional gel are shown.
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From Proteins to Proteomes: Large Scale Protein Identification by Two-Dimensional Electrophoresis and Amino Acid Analysis
Marc R. Wilkins,Christian Pasquali,Ron D. Appel,Keli Ou,Olivier Golaz,Jean-Charles Sanchez,Jun X. Yan,Andrew A. Gooley,Graham J. Hughes,Ian Humphery-Smith,Keith L. Williams,Denis F. Hochstrasser +11 more
TL;DR: Single protein spots, from polyvinylidene difluoride blots of micropreparative E. coli 2-D gels, were rapidly and economically identified by matching their amino acid composition, estimated pI and molecular weight against all E. bacteria entries in the SWISS-PROT database.
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The dynamic range of protein expression: a challenge for proteomic research.
TL;DR: It is believed that most of the existing technology is capable of displaying many more proteins than is currently achievable by integrating existing and new techniques to prefractionate samples prior to 2‐DE display or analysis.