J
Jean L. Rouleau
Researcher at Université de Montréal
Publications - 226
Citations - 51411
Jean L. Rouleau is an academic researcher from Université de Montréal. The author has contributed to research in topics: Heart failure & Ejection fraction. The author has an hindex of 72, co-authored 183 publications receiving 46536 citations. Previous affiliations of Jean L. Rouleau include Columbia University & Université de Sherbrooke.
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Journal ArticleDOI
The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels
Frank M. Sacks,Marc A. Pfeffer,Lemuel A. Moyé,Jean L. Rouleau,John D. Rutherford,Thomas G. Cole,Lisa E. Brown,J. W. Warnica,J. M. O. Arnold,Chuan Chuan C Wun,Barry R. Davis,Eugene Braunwald +11 more
TL;DR: It is demonstrated that the benefit of cholesterol-lowering therapy extends to the majority of patients with coronary disease who have average cholesterol levels and was also greater in patients with higher pretreatment levels of LDL cholesterol.
Journal ArticleDOI
Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. results of the survival and ventricular enlargement trial
Marc A. Pfeffer,Eugene Braunwald,Lemuel A. Moyé,Lofty L. Basta,Edward J. Brown,Thomas E. Cuddy,Barry R. Davis,Edward M. Geltman,Steven Goldman,Greg C. Flaker,Marc Klein,Gervasio A. Lamas,Milton Packer,Jacques R. Rouleau,Jean L. Rouleau,John D. Rutherford,John H. Wertheimer,C. Morton Hawkins +17 more
TL;DR: In patients with asymptomatic left ventricular dysfunction after myocardial infarction, long-term administration of captopril was associated with an improvement in survival and reduced morbidity and mortality due to major cardiovascular events.
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Angiotensin-neprilysin inhibition versus enalapril in heart failure.
John J.V. McMurray,Milton Packer,Akshay S. Desai,Jianjian Gong,Martin Lefkowitz,Adel R. Rizkala,Jean L. Rouleau,Victor Shi,Scott D. Solomon,Karl Swedberg,Michael R. Zile,Abstr Act +11 more
TL;DR: LCZ696 was superior to enalapril in reducing the risks of death and of hospitalization for heart failure and decreased the symptoms and physical limitations of heart failure.
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Intensive versus moderate lipid lowering with statins after acute coronary syndromes.
Christopher P. Cannon,Eugene Braunwald,Carolyn H. McCabe,Daniel J. Rader,Jean L. Rouleau,Rene Belder,Steven V. Joyal,Karen A. Hill,Marc A. Pfeffer,Allan M. Skene +9 more
TL;DR: Among patients who have recently had an acute coronary syndrome, an intensive lipid-lowering statin regimen provides greater protection against death or major cardiovascular events than does a standard regimen.
Journal ArticleDOI
Cardiac-Resynchronization Therapy for Mild-to-Moderate Heart Failure
Anthony S.L. Tang,George A. Wells,Mario Talajic,Malcolm Arnold,Robert S. Sheldon,Stuart J. Connolly,Stefan H. Hohnloser,Graham Nichol,David H. Birnie,John L. Sapp,Raymond Yee,Jeff S. Healey,Jean L. Rouleau +12 more
TL;DR: Among patients with NYHA class II or III heart failure, a wide QRS complex, and left ventricular systolic dysfunction, the addition of CRT to an ICD reduced rates of death and hospitalization for heart failure.