J
Jean Leone
Publications - 5
Citations - 875
Jean Leone is an academic researcher. The author has contributed to research in topics: Rituximab & Lupus erythematosus. The author has an hindex of 5, co-authored 5 publications receiving 805 citations.
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Journal ArticleDOI
Safety and efficacy of rituximab in systemic lupus erythematosus: Results from 136 patients from the French autoimmunity and rituximab registry
Benjamin Terrier,Zahir Amoura,Philippe Ravaud,Eric Hachulla,Romain Jouenne,Bernard Combe,Christine Bonnet,Patrice Cacoub,Alain Cantagrel,Michel De Bandt,Olivier Fain,Bruno Fautrel,Philippe Gaudin,Bertrand Godeau,Jean-Robert Harlé,Arnaud Hot,Jean-Emmanuel Kahn,Olivier Lambotte,Claire Larroche,Jean Leone,Olivier Meyer,Béatrice Pallot-Prades,Edouard Pertuiset,Pierre Quartier,Thierry Schaerverbeke,Jean Sibilia,A. Somogyi,Martin Soubrier,Eric Vignon,Brigitte Bader-Meunier,Xavier Mariette,Jacques-Eric Gottenberg +31 more
TL;DR: Data from the AIR registry show a satisfactory tolerance profile and clinical efficacy of RTX in patients with SLE, leaving open the question of the therapeutic use of RTX in SLE.
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Efficacy of rituximab in systemic manifestations of primary Sjögren's syndrome: results in 78 patients of the AutoImmune and Rituximab registry
Jacques-Eric Gottenberg,Gaël Cinquetti,Claire Larroche,Bernard Combe,Eric Hachulla,Olivier Meyer,Edouard Pertuiset,Guy Kaplanski,Laurent Chiche,Jean-Marie Berthelot,Bruno Gombert,Philippe Goupille,Christian Marcelli,Séverine Feuillet,Jean Leone,Jean Sibilia,Charles Zarnitsky,Philippe Carli,S. Rist,Philippe Gaudin,Carine Salliot,Muriel Piperno,Adeline Deplas,Maxime Breban,Thierry Lequerré,Pascal Richette,Charles Ghiringhelli,Mohamed Hamidou,Philippe Ravaud,Xavier Mariette +29 more
TL;DR: This prospective study shows good efficacy and tolerance of rituximab in patients with pSS and systemic involvement, which is mostly restricted to patients with systemic involvement.
Journal Article
Treatment of severe immune thrombocytopenia associated with systemic lupus erythematosus: 59 cases
Christophe Arnal,Jean-Charles Piette,Jean Leone,Bruno Taillan,Eric Hachulla,Françoise Roudot-Thoraval,Thomas Papo,Annette Schaeffer,Philippe Bierling,Bertrand Godeau +9 more
TL;DR: Longterm remission was obtained in the majority of patients, mainly as a result of splenectomy or combined treatment with prednisone and either danazol or hydroxychloroquine.
Journal ArticleDOI
Efficacy of rituximab in primary Sjogren's syndrome with peripheral nervous system involvement: results from the AIR registry
Arsène Mekinian,P. Ravaud,Pierre-Yves Hatron,Claire Larroche,Jean Leone,B. Gombert,M. Hamidou,Alain Cantagrel,Christian Marcelli,S. Rist,Maxime Breban,D. Launay,Olivier Fain,J.-E. Gottenberg,Xavier Mariette +14 more
TL;DR: RTX seems effective in cryoglobulinaemia or vasculitis-related PNS involvement in pSS and Rankin and European Sjögren's Syndrome Disease Activity Index scales decreased significantly in group 1.
Journal ArticleDOI
Incidence and Risk Factors of Legionella pneumophila Pneumonia During Anti-Tumor Necrosis Factor Therapy: A Prospective French Study
Fanny Lanternier,Florence Tubach,Florence Tubach,Philppe Ravaud,Dominique Salmon,Pierre Dellamonica,Stéphane Bretagne,Marie Couret,Béatrice Bouvard,Michel Debandt,Isabelle Gueit,Jean-Pierre Gendre,Jean Leone,Nathalie Nicolas,Dider Che,Xavier Mariette,Xavier Mariette,Olivier Lortholary +17 more
TL;DR: The incidence and risk factors of legionellosis associated with tumor necrosis factor (TNF)-α antagonist use are described and the risk is higher for patients receiving anti-TNF-α monoclonal antibodies than soluble TNF-receptor therapy.