J
Jean-Marc Rolain
Researcher at Aix-Marseille University
Publications - 646
Citations - 36428
Jean-Marc Rolain is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Colistin & Antibiotic resistance. The author has an hindex of 71, co-authored 601 publications receiving 30689 citations. Previous affiliations of Jean-Marc Rolain include Institut de recherche pour le développement & Institute of Tropical Medicine Antwerp.
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Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial.
Philippe Gautret,Jean-Christophe Lagier,Philippe Parola,Van Thuan Hoang,Line Meddeb,M. Mailhe,Barbara Doudier,Johan Courjon,Valérie Giordanengo,Vera Esteves Vieira,Hervé Tissot Dupont,Stéphane Honoré,Philippe Colson,Eric Chabrière,Bernard La Scola,Jean-Marc Rolain,Philippe Brouqui,Didier Raoult +17 more
TL;DR: Hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin, which was significantly more efficient for virus elimination.
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Ongoing Revolution in Bacteriology: Routine Identification of Bacteria by Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry
Piseth Seng,Michel Drancourt,Freédésrique Gouriet,Bernard La Scola,Pierre-Edouard Fournier,Jean-Marc Rolain,Didier Raoult +6 more
TL;DR: In this article, the authors used matrix assisted laser desorption ionization time-of-flight (MALDI-TOF) to identify both selected bacteria and bacteria in select clinical situations.
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ARG-ANNOT, a New Bioinformatic Tool To Discover Antibiotic Resistance Genes in Bacterial Genomes
Sushim K. Gupta,Babu Roshan Padmanabhan,Seydina M. Diene,Rafael López-Rojas,Marie Kempf,Luce Landraud,Jean-Marc Rolain +6 more
TL;DR: A concise database for BLAST using a Bio-Edit interface that can detect AR genetic determinants in bacterial genomes and can rapidly and easily discover putative new AR geneticeterminants is created.
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Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria
TL;DR: Current knowledge concerning the different strategies bacteria employ to resist the activities of polymyxins are summarized and increased understanding of these mechanisms is extremely vital and timely to facilitate studies of antimicrobial peptides and find new potential drugs targeting clinically relevant Gram-negative bacteria.
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New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?
TL;DR: The possible mechanisms of chloroquine interference with the SARS-CoV-2 replication cycle are discussed, which could lead to new therapies able to counter the most severe effects of the disease.