J
Jean-Michel Bouler
Researcher at University of Nantes
Publications - 127
Citations - 7110
Jean-Michel Bouler is an academic researcher from University of Nantes. The author has contributed to research in topics: Calcium & Bone regeneration. The author has an hindex of 44, co-authored 126 publications receiving 6440 citations. Previous affiliations of Jean-Michel Bouler include French Institute of Health and Medical Research & Atlantic University.
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Macroporous biphasic calcium phosphate ceramics: influence of macropore diameter and macroporosity percentage on bone ingrowth
TL;DR: MBCP implants with 565 microm pore diameter and 40% macroporosity represented the optimal association for homogeneous and abundant bone ingrowth and provided more abundant newly formed bone both in peripheral and deep pores.
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Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties.
TL;DR: An overview on the chemistry, kinetics of setting and handling properties (setting time, cohesion and injectability) of CPCs for bone substitution, with a focus on their mechanical properties shows that, although the mechanical strength of CPC's is generally low, it is not a critical issue for their application for bone repair.
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Osteoclastic resorption of calcium phosphate ceramics with different hydroxyapatite/β-tricalcium phosphate ratios
TL;DR: It would appear that ceramic solubility influences osteoclast resorption activity, with osteoclasts resorbed BCP most extensively, with an HA/beta-TCP ratio of 25/75, producing typical lobulated, zig-zag track-like resorptive lacunae.
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Biphasic calcium phosphate ceramics for bone reconstruction: A review of biological response.
TL;DR: The most significant biological responses reported in the last 30years, of these BCP-based materials are reviewed to discuss about their exciting future applications as osteoconductive scaffold for delivering various bioactive molecules or bone cells in bone tissue engineering and regenerative medicine.
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Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration
Bastian Peter,Dominique P. Pioletti,Samia Laïb,Bruno Bujoli,Paul Pilet,Pascal Janvier,Jérôme Guicheux,Pierre-Yves Zambelli,Jean-Michel Bouler,Olivier Gauthier +9 more
TL;DR: The obtained results open the way of an easy transformation of currently existing HA-coated implants by grafting bisphosphonate onto the coating in order to increase their service life in the patients.