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Jean-Philippe Antignac

Researcher at Institut national de la recherche agronomique

Publications -  196
Citations -  7944

Jean-Philippe Antignac is an academic researcher from Institut national de la recherche agronomique. The author has contributed to research in topics: Medicine & Mass spectrometry. The author has an hindex of 46, co-authored 171 publications receiving 6392 citations. Previous affiliations of Jean-Philippe Antignac include Paris Descartes University & École Normale Supérieure.

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The ion suppression phenomenon in liquid chromatography–mass spectrometry and its consequences in the field of residue analysis

TL;DR: In this paper, the authors present the origins and mechanisms of ion suppression, expose several case studies illustrating its consequences in the field of residue analysis, and finally, propose and comment on some solutions that may overcome this problem.
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Toxicological Function of Adipose Tissue: Focus on Persistent Organic Pollutants

TL;DR: In this paper, the authors examined the evidence that an additional function of adipose tissue is to modulate persistent organic pollutant (POP) toxicity through several mechanisms, and provided a comprehensive model for this additional function.

Toxicological function of adipose tissue: focus on persistent organic pollutants.

TL;DR: Adipose tissue appears to play diverse functions both as a modulator and as a target of POPs toxicity, particularly relevant because many POPs induce obesogenic effects that may lead to quantitative and qualitative alterations of AT.
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Exposure assessment of French women and their newborns to tetrabromobisphenol-A: Occurrence measurements in maternal adipose tissue, serum, breast milk and cord serum

TL;DR: A French monitoring study to evaluate the exposure of fetus and newborn to brominated flame retardants found a significant exposure to TBBPA both for mothers and fetuses and a possible risk of overexposure of newborns through breastfeeding.
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Fate and complex pathogenic effects of dioxins and polychlorinated biphenyls in obese subjects before and after drastic weight loss.

TL;DR: Drastic weight loss leads to a redistribution of POPs and to a moderate decrease of their total body burden, and serum POP levels were positively correlated with liver toxicity markers and lipid parameters, independently of age and body mass index.