Jeena Rajan

TL;DR: This work has examined the completeness of the transcript annotation and found that 35% of transcriptional start sites are supported by CAGE clusters and 62% of protein-coding genes have annotated polyA sites, and over one-third of GENCODE protein-Coding genes aresupported by peptide hits derived from mass spectrometry spectra submitted to Peptide Atlas.

TL;DR: The CCDS database centralizes the function of identifying well-supported, identically-annotated, protein-coding regions and indicates that the entries in the CCDS set are highly likely to represent real proteins, more so than annotations from contributing groups not included in CCDS.

TL;DR: The finished sequence and biological annotation of human chromosome 1 is reported, which reveals patterns of sequence variation that reveal signals of recent selection in specific genes that may contribute to human fitness, and also in regions where no function is evident.

TL;DR: The current status and recent growth in the CCDS dataset is described, as well as recent changes to the web and FTP sites, which include more explicit reporting about the NCBI and Ensembl annotation releases being compared, new search and display options, the addition of biologically descriptive information and the approach to representing genes for which support evidence is incomplete.

TL;DR: Making the world’s public sequencing datasets available to the scientific community, the ENA represents a globally comprehensive nucleotide sequence resource in 2019 and provides an insight into selected key areas of development.