Showing papers by "Jefferson A. Vaughan published in 2009"
TL;DR: A phylogenetic analysis using molecular characters places the new species in the basal clade of tetrapod blood flukes, more derived than Spirhapalum polesianum, but lessderived than Spirorchis spp.
Abstract: Spirhapalum siamensis n. sp. obtained from the heart of the Malayan box turtle, Cuora amboinensis, from western Thailand is described. This blood fluke differs from the 2 previously known species of Spirhapalum in its larger overall body size, constricted mid-body, greater number of pre-ovarian testes, ceca that loop anteriorly from the cecal bifurcation before turning to the posterior, and the relatively smaller size of its ventral sucker. A phylogenetic analysis using molecular characters places the new species in the basal clade of tetrapod blood flukes, more derived than Spirhapalum polesianum, but less derived than Spirorchis spp.
11 citations
TL;DR: Results indicated that, over the 14-year simulation period, mf-induced acceleration of the EIP would generate more frequent (but not necessarily more severe) epidemics.
Abstract: Concurrent ingestion of microfilariae (mf) and arboviruses by mosquitoes can enhance the transmission of virus compared with when virus is ingested alone. We studied the effect of mf enhancement on the extrinsic incubation period (EIP) of dengue 1 virus within Aedes aegypti mosquitoes by feeding mosquitoes on blood that either contained virus plus Brugia malayi mf or virus only. Mosquitoes were sampled over time to determine viral dissemination rates. Co-ingestion of mf and virus reduced viral EIP by over half. We used the computer simulation program, DENSiM, to compare the predicted patterns of dengue incidence that would result from such a shortened EIP versus the EIP derived from the control (i.e., virus only) group of mosquitoes. Results indicated that, over the 14-year simulation period, mf-induced acceleration of the EIP would generate more frequent (but not necessarily more severe) epidemics. Potential interactions between arboviruses and hematozoans deserve closer scrutiny.
10 citations