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Jefferson A. Vaughan

Researcher at University of North Dakota

Publications -  57
Citations -  1835

Jefferson A. Vaughan is an academic researcher from University of North Dakota. The author has contributed to research in topics: Population & Anopheles gambiae. The author has an hindex of 23, co-authored 53 publications receiving 1632 citations. Previous affiliations of Jefferson A. Vaughan include United States Department of the Army & Johns Hopkins University.

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Comparison of PCR and microscopy for the detection of asymptomatic malaria in a Plasmodium falciparum/vivax endemic area in Thailand

TL;DR: PCR appears to be a useful method for detecting Plasmodium parasites during active malaria surveillance in Thailand, and data indicated that the discrepancy between the two methods resulted from poor performance of microscopy at low parasite densities rather thanpoor performance of PCR.
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Population dynamics of Plasmodium falciparum sporogony in laboratory-infected Anopheles gambiae.

TL;DR: This quantitative study indicates that the sporogony of cultured P. falciparum in laboratory-infected A. gambiae is an inefficient process and that the ookinete is the key transitional stage affecting the probability of vector infectivity.
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Quantitation of Plasmodium falciparum sporozoites transmitted in vitro by experimentally infected Anopheles gambiae and Anopheles stephensi.

TL;DR: The low but highly variable numbers of sporozoites transmitted in vitro by mosquitoes used in malaria vaccine challenge studies appears to be a reasonable simulation of natural sporozoite transmission.
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Population dynamics of Plasmodium sporogony.

TL;DR: Recent publications on the population dynamics of sporogony are reviewed, with special attention to the differences and similarities among the parasite-vector systems examined thus far.
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Anti-mosquito midgut antibodies block development of plasmodium falciparum and plasmodium vivax in multiple species of anopheles mosquitoes and reduce vector fecundity and survivorship

TL;DR: The results reveal that mosquito midgut-based antibodies have the potential to reduce malaria transmission in a synergistic manner by lowering both vector competence, through transmission-blocking effects on parasite development, and vector abundance, by decreasing mosquito survivorship and egg laying capacity.