Showing papers by "Jeffrey W. Kysar published in 2015"
TL;DR: This work provides strong evidence supporting the importance of intermolecular interactions through the use of NPs grafted with polymers that can hydrogen bond with the matrix, yielding to significant improvements in the measured mechanical properties.
Abstract: It is now well accepted that the addition of nanoparticles (NPs) can strongly affect the thermomechanical properties of the polymers into which they are incorporated. In the solid (glassy) state, previous work has implied that optimal mechanical properties are achieved when the NPs are well dispersed in the matrix and when there is strong interfacial binding between the grafted NPs and the polymer matrix. Here we provide strong evidence supporting the importance of intermolecular interactions through the use of NPs grafted with polymers that can hydrogen bond with the matrix, yielding to significant improvements in the measured mechanical properties. Our finding thus supports the previously implied central role of strong interfacial binding in optimizing the mechanical properties of polymer nanocomposites.
52 citations
TL;DR: Diffusion cells can be applied to the study of RWM permeability in vitro and microperforation in RWM is an effective means of increasing diffusion across the RWM.
Abstract: Hypothesis
Introduction of microperforations in round window membrane (RWM) will allow reliable and predictable intracochlear delivery of pharmaceutical, molecular or cellular therapeutic agents.
39 citations
Patent•
29 Jun 20151 citations