J
Jennifer Moyle
Researcher at University of Cambridge
Publications - 26
Citations - 2775
Jennifer Moyle is an academic researcher from University of Cambridge. The author has contributed to research in topics: Respiratory chain & Calcium. The author has an hindex of 25, co-authored 26 publications receiving 2710 citations.
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Journal ArticleDOI
Respiration-driven proton translocation in rat liver mitochondria
Peter Mitchell,Jennifer Moyle +1 more
TL;DR: Stoicheiometric acid-base changes associated with the activity of the regions of the respiratory chain on the oxygen side of the rotenone- and antimycin A-sensitive sites gives experimental support for a suggested configuration of loop 3.
Journal ArticleDOI
Acid–base titration across the membrane system of rat-liver mitochondria: Catalysis by uncouplers
Peter Mitchell,Jennifer Moyle +1 more
TL;DR: Pulsed acid-base titrations of suspensions of rat-liver mitochondria under anaerobic equilibrium conditions show fast and slow titration processes that will account quantitatively for the observed respiratory control in state 4, assuming that oxidoreduction and phosphorylation are coupled by a circulating proton current as required by the chemi-osmotic hypothesis.
Journal ArticleDOI
Chemiosmotic hypothesis of oxidative phosphorylation.
Peter Mitchell,Jennifer Moyle +1 more
TL;DR: Critics of their interpretation of tests of the hypothesis proposed by Dr. Moyle and Dr. Mitchell to explain ATP synthesis in the inner membrane of mitochondria and of chloroplasts by a fuel-cell type of mechanism are answered.
Journal ArticleDOI
Stoichiometry of Proton Translocation through the Respiratory Chain and Adenosine Triphosphatase Systems of Rat Liver Mitochondria
Peter Mitchell,Jennifer Moyle +1 more
TL;DR: Stoichiometry of Proton Translocation through the Respiratory Chain and Adenosine Triphosphatase Systems of Rat Liver Mitochondria shows good correspondence with known proton-proton transfer mechanisms.
Journal ArticleDOI
Evidence discriminating between the Chemical and the Chemiosmotic Mechanisms of Electron Transport Phosphorylation
Peter Mitchell,Jennifer Moyle +1 more
TL;DR: More crucial experimental tests of the alternative hypotheses are sought of the proton pump driven by hydrolysis of X ∼ I, either directly, or via the ‘W complex’ suggested by Lardy, Connelly and Johnson.