scispace - formally typeset
J

Jens R. Wendland

Researcher at Pfizer

Publications -  75
Citations -  15819

Jens R. Wendland is an academic researcher from Pfizer. The author has contributed to research in topics: Genome-wide association study & Serotonin transporter. The author has an hindex of 41, co-authored 74 publications receiving 13459 citations. Previous affiliations of Jens R. Wendland include Valparaiso University & United States Department of Health and Human Services.

Papers
More filters
Journal ArticleDOI

Biological insights from 108 schizophrenia-associated genetic loci

Stephan Ripke, +354 more
- 24 Jul 2014 - 
TL;DR: Associations at DRD2 and several genes involved in glutamatergic neurotransmission highlight molecules of known and potential therapeutic relevance to schizophrenia, and are consistent with leading pathophysiological hypotheses.
Journal ArticleDOI

Analysis of shared heritability in common disorders of the brain

Verneri Anttila, +720 more
- 22 Jun 2018 - 
TL;DR: It is demonstrated that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine, and it is shown that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures.
Journal ArticleDOI

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Bjarni J. Vilhjálmsson, +394 more
- 01 Oct 2015 - 
TL;DR: LDpred is introduced, a method that infers the posterior mean effect size of each marker by using a prior on effect sizes and LD information from an external reference panel, and outperforms the approach of pruning followed by thresholding, particularly at large sample sizes.
Journal ArticleDOI

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

Craig L. Hyde, +9 more
- 01 Sep 2016 - 
TL;DR: These studies provide evidence for large-scale consumer genomic data as a powerful and efficient complement to data collected from traditional means of ascertainment for neuropsychiatric disease genomics.
Journal ArticleDOI

Simultaneous genotyping of four functional loci of human SLC6A4, with a reappraisal of 5-HTTLPR and rs25531.

Jens R. Wendland, +4 more
- 01 Mar 2006 - 
TL;DR: Simultaneous genotyping of four functional loci of human SLC6A4 , with a reappraisal of 5-HTTLPR and rs25531 shows good agreement with previous work on this topic.