J
Jeongbin Yim
Researcher at Seoul National University
Publications - 56
Citations - 7199
Jeongbin Yim is an academic researcher from Seoul National University. The author has contributed to research in topics: Gene & Telomerase reverse transcriptase. The author has an hindex of 20, co-authored 53 publications receiving 6808 citations. Previous affiliations of Jeongbin Yim include University of Pennsylvania & Soonchunhyang University.
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Journal ArticleDOI
The nuclear RNase III Drosha initiates microRNA processing
Yoontae Lee,Chiyoung Ahn,Jinju Han,Hyounjeong Choi,Jaekwang Kim,Jeongbin Yim,Junho Lee,Patrick Provost,Olof Rådmark,Sun-Young Kim,V. Narry Kim +10 more
TL;DR: The two RNase III proteins, Drosha and Dicer, may collaborate in the stepwise processing of miRNAs, and have key roles in miRNA-mediated gene regulation in processes such as development and differentiation.
Journal ArticleDOI
A TRPV family ion channel required for hearing in Drosophila
Janghwan Kim,Yun Doo Chung,Dae-young Park,SooKyung Choi,Dong Wook Shin,Heun Soh,Hye Won Lee,Wonseok Son,Jeongbin Yim,Chul-Seung Park,Maurice J. Kernan,Changsoo Kim +11 more
TL;DR: The Drosophila Nanchung (Nan) protein is described, an ion channel subunit similar to vanilloid-receptor-related (TRPV) channels of the TRP superfamily that mediates hypo-osmotically activated calcium influx and cation currents in cultured cells and is localized to their sensory cilia.
Journal ArticleDOI
Sp1 and Sp3 Recruit Histone Deacetylase to Repress Transcription of Human Telomerase Reverse Transcriptase (hTERT) Promoter in Normal Human Somatic Cells
TL;DR: Results suggest that Sp1 and Sp3 associate with the h TERT promoter, recruiting HDAC for the localized deacetylation of nucleosomal histones and transcriptional silencing of the hTERT gene in normal human somatic cells.
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Identification of Mad as a repressor of the human telomerase (hTERT) gene.
TL;DR: Mad may be a direct negative regulator of hTERT in mortal cells and this repression mechanism can be inhibited by induction of Myc in immortal cells.
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The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene
TL;DR: The results suggest that WT1 may be a transcriptional repressor of the hTERT gene, at least in some specific cells, and identify cDNAs whose products can repress h TERT promoter activity in telomerase-positive immortal cells.