J
Jeremy W. Tomlinson
Researcher at University of Oxford
Publications - 254
Citations - 15420
Jeremy W. Tomlinson is an academic researcher from University of Oxford. The author has contributed to research in topics: Adipose tissue & Glucocorticoid. The author has an hindex of 58, co-authored 211 publications receiving 12878 citations. Previous affiliations of Jeremy W. Tomlinson include Churchill Hospital & University of Edinburgh.
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Journal ArticleDOI
Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
Matthew J. Armstrong,Matthew J. Armstrong,Piers Gaunt,Guruprasad P. Aithal,Darren Barton,Darren Barton,Diana Hull,Diana Hull,Richard D. Parker,Richard D. Parker,Jonathan Hazlehurst,Kathy Guo,Kathy Guo,G. Abouda,M. Aldersley,Deborah D. Stocken,Stephen C. L. Gough,Jeremy W. Tomlinson,Rachel M. Brown,Stefan G. Hübscher,Stefan G. Hübscher,Philip N. Newsome,Philip N. Newsome +22 more
TL;DR: Liraglutide was safe, well tolerated, and led to histological resolution of non-alcoholic steatohepatitis, warranting extensive, longer-term studies.
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11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.
Jeremy W. Tomlinson,Elizabeth A. Walker,Iwona J. Bujalska,Nicole Draper,Gareth G. Lavery,Mark S. Cooper,Martin Hewison,Paul M. Stewart +7 more
TL;DR: It is speculated that hexose-6-phosphate dehydrogenase activity and therefore reduced nicotinamide-adenine dinucleotide phosphate supply may be crucial in determining the directionality of 11beta-HSD1 activity.
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Association between premature mortality and hypopituitarism
Jeremy W. Tomlinson,N. Holden,Robert Kerrin Hills,Keith Wheatley,Richard N. Clayton,A. S. Bates,Michael C. Sheppard,Paul M. Stewart +7 more
TL;DR: Age at diagnosis, female sex, and above all, craniopharyngioma were significant independent risk factors and specific endocrine-axis deficiency, with the exception of untreated gonadotropin deficiency, does not seem to have a role.
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Effects of interventions in pregnancy on maternal weight and obstetric outcomes: meta-analysis of randomised evidence
Shakila Thangaratinam,Ewelina Rogozińska,Kate Jolly,S Glinkowski,Tessa J. Roseboom,Jeremy W. Tomlinson,Regina Kunz,Ben W.J. Mol,Arri Coomarasamy,Khalid S. Khan +9 more
TL;DR: Dietary interventions based on diet are the most effective and are associated with reductions in maternal gestational weight gain and improved obstetric outcomes and the overall evidence rating was low to very low for important outcomes such as pre-eclampsia, Gestational diabetes, gestational hypertension, and preterm delivery.
Journal ArticleDOI
Pathogenesis of non-alcoholic fatty liver disease
TL;DR: NAFLD has a strong association with type 2 diabetes, with steatosis present in 70% of type 2 diabetics screened with ultrasound, and thus it is now recognized to represent the hepatic manifestation of the metabolic syndrome.