J
Jeroen Raes
Researcher at Katholieke Universiteit Leuven
Publications - 293
Citations - 85097
Jeroen Raes is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Microbiome & Medicine. The author has an hindex of 84, co-authored 240 publications receiving 66805 citations. Previous affiliations of Jeroen Raes include Flanders Institute for Biotechnology & Université catholique de Louvain.
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Journal ArticleDOI
Species–function relationships shape ecological properties of the human gut microbiome
Sara Vieira-Silva,Gwen Falony,Youssef Darzi,Youssef Darzi,Gipsi Lima-Mendez,Gipsi Lima-Mendez,Roberto Garcia Yunta,Roberto Garcia Yunta,Shujiro Okuda,Doris Vandeputte,Doris Vandeputte,Mireia Valles-Colomer,Falk Hildebrand,Falk Hildebrand,Samuel Chaffron,Samuel Chaffron,Jeroen Raes,Jeroen Raes +17 more
TL;DR: It was found that module-derived functional redundancy was reduced in the low-richness Bacteroides enterotype, potentially indicating a decreased resilience to perturbation, in line with its frequent association to dysbiosis.
Journal ArticleDOI
Towards microbial fermentation metabolites as markers for health benefits of prebiotics
Kristin Verbeke,Alan R. Boobis,Alessandro Chiodini,Christine A. Edwards,Anne Franck,Michiel Kleerebezem,Arjen Nauta,Jeroen Raes,Eric A.F. van Tol,Kieran Tuohy +9 more
TL;DR: There is insufficient evidence to use changes in faecal bacterial metabolite concentrations as markers of prebiotic effectiveness, and adequate tools for data integration and interpretation are currently lacking.
Journal ArticleDOI
Donor Species Richness Determines Faecal Microbiota Transplantation Success in Inflammatory Bowel Disease.
Severine Vermeire,Marie Joossens,Marie Joossens,Kristin Verbeke,Jun Wang,Kathleen Machiels,João Sabino,Marc Ferrante,Gert Van Assche,Paul Rutgeerts,Jeroen Raes +10 more
TL;DR: Faecal microbiota transplantation with donor prescreening led to endoscopic and long-term (>2 years) remission in 2 out of 8 ulcerative colitis patients and higher donor richness was associated with successful transplant.
Journal ArticleDOI
LotuS: an efficient and user-friendly OTU processing pipeline
Falk Hildebrand,Falk Hildebrand,Falk Hildebrand,Raul Yhossef Tito Tadeo,Anita Y. Voigt,Anita Y. Voigt,Peer Bork,Jeroen Raes +7 more
TL;DR: It is shown that LotuS analyses microbial 16S data with comparable or even better results than existing pipelines, requiring a fraction of the execution time and providing state-of-the-art denoising and phylogenetic reconstruction.
Journal ArticleDOI
Assessment of metagenomic assembly using simulated next generation sequencing data.
Daniel R. Mende,Alison S. Waller,Shinichi Sunagawa,Aino I Järvelin,Michelle Chan,Manimozhiyan Arumugam,Jeroen Raes,Peer Bork +7 more
TL;DR: This research developed metagenomic read simulators with platform-specific (Sanger, pyrosequencing, Illumina) base-error models, and simulated metagenomes of differing community complexities, and examined the effect of rigorous quality control on Illumina data.