J
Jeroen Raes
Researcher at Katholieke Universiteit Leuven
Publications - 293
Citations - 85097
Jeroen Raes is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Microbiome & Medicine. The author has an hindex of 84, co-authored 240 publications receiving 66805 citations. Previous affiliations of Jeroen Raes include Flanders Institute for Biotechnology & Université catholique de Louvain.
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Journal ArticleDOI
Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients With Inflammatory Bowel Diseases
Konrad Aden,Ateequr Rehman,Silvio Waschina,Wei-Hung Pan,Alesia Walker,Marianna Lucio,Alejandro Mena Nunez,Richa Bharti,Johannes Zimmerman,Johannes Bethge,Berenice Schulte,Dominik M. Schulte,Andre Franke,Susanna Nikolaus,Johann O. Schroeder,Doris Vandeputte,Jeroen Raes,Silke Szymczak,Georg H. Waetzig,R Zeuner,Philippe Schmitt-Kopplin,Christoph Kaleta,Stefan Schreiber,Philip Rosenstiel +23 more
TL;DR: Metabolic network reconstruction and assessment of metabolic profiles of fecal samples might be used to identify patients with IBD likely to achieve clinical remission following anti-TNF therapy and increase the understanding of the heterogeneity of IBD.
Journal ArticleDOI
Millimeter-scale genetic gradients and community-level molecular convergence in a hypersaline microbial mat.
Victor Kunin,Jeroen Raes,J. Kirk Harris,John R. Spear,Jeffrey J. Walker,Natalia Ivanova,Christian von Mering,Brad M. Bebout,Norman R. Pace,Peer Bork,Philip Hugenholtz +10 more
TL;DR: All layers of a phylogenetically complex hypersaline mat displayed near‐identical and acid‐shifted isoelectric point profiles due to a molecular convergence of amino‐acid usage, indicating that hypersalinity enforces an overriding selective pressure on the mat community.
Journal ArticleDOI
Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity.
Lore Vanderbeke,P. Van Mol,Y. Van Herck,F. De Smet,Stephanie Humblet-Baron,Kimberly Martinod,Asier Antoranz,Ingrid Arijs,Bram Boeckx,Francesca Maria Bosisio,M. Casaer,Dieter Dauwe,W. De Wever,Christophe Dooms,Erwin Dreesen,A. Emmaneel,J. Filtjens,M. Gouwy,Jan Gunst,Greet Hermans,Steven Jansen,Katrien Lagrou,Adrian Liston,N. Lorent,Philippe Meersseman,Toine Mercier,Johan Neyts,J. Odent,Dena Panovska,P. A. Penttila,E. Pollet,Paul Proost,Junbin Qian,K. Quintelier,Jeroen Raes,S. Rex,Yvan Saeys,Jenny Sprooten,Sabine Tejpar,Dries Testelmans,Karin Thevissen,T. Van Buyten,J. Vandenhaute,S. Van Gassen,L. C. Velásquez Pereira,R. Vos,Birgit Weynand,A. Wilmer,Jonas Yserbyt,Abhishek D. Garg,Patrick Matthys,Carine Wouters,D Lambrechts,Els Wauters,Joost Wauters +54 more
TL;DR: A myeloid-driven immunopathology is suggested, in which hyperactivated neutrophils and an ineffective adaptive immune system act as mediators of COVID-19 disease severity.
Journal ArticleDOI
Soil microbiome responses to the short‐term effects of Amazonian deforestation
Acacio Aparecido Navarrete,Siu Mui Tsai,Lucas William Mendes,Karoline Faust,Mattias de Hollander,Noriko A. Cassman,Jeroen Raes,Johannes A. van Veen,Eiko E. Kuramae +8 more
TL;DR: The results support taxonomic and functional adaptations in the soil bacterial community following deforestation and hypothesized that these microbial adaptations may serve as a buffer to drastic changes in soil fertility after slash‐and‐burning deforestation in the Amazon region.
Journal ArticleDOI
Cross-biome comparison of microbial association networks
Karoline Faust,Gipsi Lima-Mendez,Gipsi Lima-Mendez,Jean-Sébastien Lerat,Jarupon F. Sathirapongsasuti,Rob Knight,Curtis Huttenhower,Tom Lenaerts,Jeroen Raes,Jeroen Raes +9 more
TL;DR: An under-appreciated role of evenness is suggested in shaping microbial association networks, and it is observed that soil microbial networks harbor proportionally fewer positive associations and are less densely interconnected than host-associated networks.