J
Jeroen Raes
Researcher at Katholieke Universiteit Leuven
Publications - 293
Citations - 85097
Jeroen Raes is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Microbiome & Medicine. The author has an hindex of 84, co-authored 240 publications receiving 66805 citations. Previous affiliations of Jeroen Raes include Flanders Institute for Biotechnology & Université catholique de Louvain.
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Journal ArticleDOI
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative
Jun Wang,Jun Wang,Alexander Kurilshikov,Djawad Radjabzadeh,Williams Turpin,Williams Turpin,Kenneth Croitoru,Marc Jan Bonder,Marc Jan Bonder,Matthew A. Jackson,Carolina Medina-Gomez,Fabian Frost,Georg Homuth,Malte C. Rühlemann,David A. Hughes,Han na Kim,Tim D. Spector,Jordana T. Bell,Claire J. Steves,N J Timpson,Andre Franke,Cisca Wijmenga,Katie A. Meyer,Tim Kacprowski,Lude Franke,Andrew D. Paterson,Jeroen Raes,Robert Kraaij,Alexandra Zhernakova +28 more
TL;DR: The MiBioGen consortium initiative, which has assembled 18 population-level cohorts and some 19,000 participants, is presented, which is the largest consortium to date devoted to microbiota-GWAS and can reduce the potential artifacts introduced by technical differences in generating microbiota data.
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Quantitative assessment of protein function prediction from metagenomics shotgun sequences
Eoghan D. Harrington,Amoolya H. Singh,Tobias Doerks,Ivica Letunic,C. von Mering,Lars Juhl Jensen,Jeroen Raes,Peer Bork +7 more
TL;DR: The results suggest that, although functions can be inferred for most proteins on earth, many functions remain to be discovered in numerous small, rare protein families.
Journal ArticleDOI
Richness and ecosystem development across faecal snapshots of the gut microbiota.
TL;DR: The need to rethink microbiome biomarkers in the context of gut ecology is discussed, with a focus on gut microbiota richness and community resilience.
Journal ArticleDOI
Butyrate Producers as Potential Next-Generation Probiotics: Safety Assessment of the Administration of Butyricicoccus pullicaecorum to Healthy Volunteers
Leen Boesmans,Mireia Valles-Colomer,Jun Wang,Venessa Eeckhaut,Gwen Falony,Richard Ducatelle,Filip Van Immerseel,Jeroen Raes,Jeroen Raes,Kristin Verbeke +9 more
TL;DR: In this first human intervention trial with a butyrate-producing Clostridium cluster IV isolate, B. pullicaecorum 25-3T administration was found to be both safe and well tolerated by healthy participants, paving the way for the further development of the strain as a next-generation probiotic.
Journal ArticleDOI
Integrated culturing, modeling and transcriptomics uncovers complex interactions and emergent behavior in a three-species synthetic gut community.
Kevin D'hoe,Stefan Vet,Stefan Vet,Karoline Faust,Frédéric Moens,Gwen Falony,Didier Gonze,Verónica Lloréns-Rico,Lendert Gelens,Jan Danckaert,Luc De Vuyst,Jeroen Raes,Jeroen Raes +12 more
TL;DR: This work established a synthetic community composed of three representative human gut isolates and explored their interactions under well-controlled conditions in vitro, demonstrating that strains grown in co-culture behaved differently than those in mono-culture and confirming their altered behavior at the transcriptional level.