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Jérôme Guicheux

Researcher at University of Nantes

Publications -  257
Citations -  11079

Jérôme Guicheux is an academic researcher from University of Nantes. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell. The author has an hindex of 58, co-authored 238 publications receiving 9568 citations. Previous affiliations of Jérôme Guicheux include Université Nantes Angers Le Mans & French Institute of Health and Medical Research.

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Journal ArticleDOI

Cartilage engineering: a crucial combination of cells, biomaterials and biofactors

Claire Vinatier, +8 more
- 01 May 2009 - 
TL;DR: The requirements for identifying additional specific growth Factors and evaluating the optimal combination of cells, growth factors and scaffolds that is able to respond to the functional demand placed upon cartilage tissue replacement in clinics are discussed.
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Oxidative stress in bone remodelling and disease.

Fabien Wauquier, +4 more
- 01 Oct 2009 - 
TL;DR: The crucial role of oxidative stress in bone pathophysiology is reviewed, and the possibility that ROS production might be a relevant therapeutic target under certain conditions is discussed, to investigate whether manipulation of the redox balance in bone cells represents a useful approach in the design of future therapies for bone diseases.
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Activation of p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinase by BMP-2 and their implication in the stimulation of osteoblastic cell differentiation.

Jérôme Guicheux, +7 more
- 01 Nov 2003 - 
TL;DR: It is reported that BMP‐2 can activate JNK and p38 in osteoblastic cells and evidence is provided that these MAP kinases have distinct roles in regulating alkaline phosphatase and osteocalcin expression.
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Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration

Bastian Peter, +9 more
- 01 Jan 2005 - 
TL;DR: The obtained results open the way of an easy transformation of currently existing HA-coated implants by grafting bisphosphonate onto the coating in order to increase their service life in the patients.
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An injectable vehicle for nucleus pulposus cell-based therapy.

Estelle Collin, +8 more
- 01 Apr 2011 - 
TL;DR: The optimally stabilised and functionalised type II collagen/HA hydrogel system developed in this study shows promise as an injectable reservoir system for intervertebral disc regeneration.