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Jérôme Wenger

Bio: Jérôme Wenger is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Fluorescence correlation spectroscopy & Fluorescence spectroscopy. The author has an hindex of 44, co-authored 159 publications receiving 7362 citations. Previous affiliations of Jérôme Wenger include University of Strasbourg & École Centrale Paris.


Papers
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Journal ArticleDOI
16 Jan 2003-Nature
TL;DR: This work proposes and experimentally demonstrate a quantum key distribution protocol based on the transmission of gaussian-modulated coherent states and shot-noise-limited homodyne detection, which is in principle secure for any value of the line transmission, against gaussian individual attacks based on entanglement and quantum memories.
Abstract: Quantum continuous variables are being explored as an alternative means to implement quantum key distribution, which is usually based on single photon counting. The former approach is potentially advantageous because it should enable higher key distribution rates. Here we propose and experimentally demonstrate a quantum key distribution protocol based on the transmission of gaussian-modulated coherent states (consisting of laser pulses containing a few hundred photons) and shot-noise-limited homodyne detection; squeezed or entangled beams are not required. Complete secret key extraction is achieved using a reverse reconciliation technique followed by privacy amplification. The reverse reconciliation technique is in principle secure for any value of the line transmission, against gaussian individual attacks based on entanglement and quantum memories. Our table-top experiment yields a net key transmission rate of about 1.7 megabits per second for a loss-free line, and 75 kilobits per second for a line with losses of 3.1 dB. We anticipate that the scheme should remain effective for lines with higher losses, particularly because the present limitations are essentially technical, so that significant margin for improvement is available on both the hardware and software.

1,224 citations

Book ChapterDOI
TL;DR: This tutorial chapter is intended to give an "hands on" view of FCS, including calibration, measurement, and data treatment, and the major difficulties that are encountered when performing for the first time FCS.
Abstract: Fluorescence correlation spectroscopy (FCS), implemented in microscopy, relies on performing an autocorrelation of the time fluctuating intensity arising from individual molecules diffusing through a confocal volume. It allows us to investigate a large variety of dynamic processes and to quantify photophysical, photochemical, interaction, diffusion, and transport properties of molecules. This tutorial chapter is intended to give an "hands on" view of FCS. After a brief introduction on the principle of FCS, the major theoretical assumptions are emphasized, and the main analytical expression are given. Then the key parameters that have to be considered when building a FCS system are discussed. The complete method of operation is described, including calibration, measurement, and data treatment. The major difficulties that are encountered when performing for the first time FCS are illustrated by examples of measurements, and possible solutions are proposed.

418 citations

Journal ArticleDOI
TL;DR: The experimental observation of a degaussification protocol, mapping individual femtosecond pulses of squeezed light onto non-Gaussian states by using only simple linear optical elements is described.
Abstract: We describe the observation of a "degaussification" protocol that maps individual pulses of squeezed light onto non-Gaussian states. This effect is obtained by sending a small fraction of the squeezed vacuum beam onto an avalanche photodiode, and by conditioning the single-shot homodyne detection of the remaining state upon the photon-counting events. The experimental data provide clear evidence of phase-dependent non-Gaussian statistics. This protocol is closely related to the first step of an entanglement distillation procedure for continuous variables.

336 citations

Journal ArticleDOI
TL;DR: A novel 'antenna-in-box' platform that is based on a gap-antenna inside a nanoaperture that combines fluorescent signal enhancement and background screening, offering high single-molecule sensitivity at micromolar sample concentrations and zeptolitre-range detection volumes.
Abstract: Single molecule fluorescence techniques [1-3] are key for several applications including DNA sequencing [4, 5], molecular and cell biology [6, 7], and early diagnosis [8]. Unfortunately, observation of single molecules by diffraction-limited optics is restricted to detection volumes in the femtolitre range and imperatively requires pico-or nanomolar concentrations, far below the micromolar range where most biological reactions occur [2]. This limitation can be overcome using plasmonic nanostructures, and confinement of light down to nanoscale volumes has been reported [9-13]. While these nanoantennas enhance fluorescence brightness [14-20], large background signals [20-22] and/or unspecific binding to the metallic surface [23-25] has hampered the detection of individual fluorescent molecules in solution at high concentrations. Here we introduce a novel "antenna-in-box" platform that is based on a gap-antenna inside a nanoaperture. This design combines fluorescent signal enhancement and background screening, offering high single molecule sensitivity (fluorescence enhancement up to 1100 folds and microsecond transit time) at micromolar sample concentrations and zeptolitre-range detection volumes. The antennain-box device can be optimized for single molecule fluorescence studies at physiologicallyrelevant concentrations, as we demonstrate using various biomolecules. Our antenna-in-box design is shown in Figure 1a and b. The rationale behind our design is that in any nanoantenna experiment on molecules in solution, the observed fluorescence signal is a sum of two contributions: the enhanced fluorescence from the few molecules in the nanoantenna gap region (hot

298 citations

Journal ArticleDOI
TL;DR: The direct experimental observation of photonic nanojets created by single latex microspheres illuminated by a plane wave at a wavelength of 520 nm displays all the specificities of aPhotonic nanojet.
Abstract: We report the direct experimental observation of photonic nanojets created by single latex microspheres illuminated by a plane wave at a wavelength of 520 nm. Measurements are performed with a fast scanning confocal microscope in detection mode, where the detection pinhole defines a diffraction-limited observation volume that is scanned in three dimensions over the microsphere vicinity. From the collected stack of images, we reconstruct the full 3 dimensional photonic nanojet beam. Observations are conducted for polystyrene spheres of 1, 3 and 5 µm diameter deposited on a glass substrate, the upper medium being air or water. Experimental results are compared to calculations performed using the Mie theory. We measure nanojet sizes as small as 270 nm FWHM for a 3 µm sphere at a wavelength λ of 520 nm. The beam keeps a subwavelength FWHM over a propagation distance of more than 3 λ, displaying all the specificities of a photonic nanojet.

284 citations


Cited by
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Book
15 May 2007
TL;DR: In this paper, the authors discuss the role of surface plasmon polaritons at metal/insulator interfaces and their application in the propagation of surfaceplasmon waveguides.
Abstract: Fundamentals of Plasmonics.- Electromagnetics of Metals.- Surface Plasmon Polaritons at Metal / Insulator Interfaces.- Excitation of Surface Plasmon Polaritons at Planar Interfaces.- Imaging Surface Plasmon Polariton Propagation.- Localized Surface Plasmons.- Electromagnetic Surface Modes at Low Frequencies.- Applications.- Plasmon Waveguides.- Transmission of Radiation Through Apertures and Films.- Enhancement of Emissive Processes and Nonlinearities.- Spectroscopy and Sensing.- Metamaterials and Imaging with Surface Plasmon Polaritons.- Concluding Remarks.

7,238 citations

Journal ArticleDOI
TL;DR: The basic concepts behind plasmonics-enabled light concentration and manipulation are discussed, an attempt to capture the wide range of activities and excitement in this area is made, and possible future directions are speculated on.
Abstract: The unprecedented ability of nanometallic (that is, plasmonic) structures to concentrate light into deep-subwavelength volumes has propelled their use in a vast array of nanophotonics technologies and research endeavours. Plasmonic light concentrators can elegantly interface diffraction-limited dielectric optical components with nanophotonic structures. Passive and active plasmonic devices provide new pathways to generate, guide, modulate and detect light with structures that are similar in size to state-of-the-art electronic devices. With the ability to produce highly confined optical fields, the conventional rules for light-matter interactions need to be re-examined, and researchers are venturing into new regimes of optical physics. In this review we will discuss the basic concepts behind plasmonics-enabled light concentration and manipulation, make an attempt to capture the wide range of activities and excitement in this area, and speculate on possible future directions.

3,953 citations

Journal ArticleDOI
02 Jan 2009-Science
TL;DR: Single-molecule, real-time sequencing data obtained from a DNA polymerase performing uninterrupted template-directed synthesis using four distinguishable fluorescently labeled deoxyribonucleoside triphosphates (dNTPs) are presented.
Abstract: We present single-molecule, real-time sequencing data obtained from a DNA polymerase performing uninterrupted template-directed synthesis using four distinguishable fluorescently labeled deoxyribonucleoside triphosphates (dNTPs). We detected the temporal order of their enzymatic incorporation into a growing DNA strand with zero-mode waveguide nanostructure arrays, which provide optical observation volume confinement and enable parallel, simultaneous detection of thousands of single-molecule sequencing reactions. Conjugation of fluorophores to the terminal phosphate moiety of the dNTPs allows continuous observation of DNA synthesis over thousands of bases without steric hindrance. The data report directly on polymerase dynamics, revealing distinct polymerization states and pause sites corresponding to DNA secondary structure. Sequence data were aligned with the known reference sequence to assay biophysical parameters of polymerization for each template position. Consensus sequences were generated from the single-molecule reads at 15-fold coverage, showing a median accuracy of 99.3%, with no systematic error beyond fluorophore-dependent error rates.

3,346 citations

01 Jan 2016
TL;DR: The principles of fluorescence spectroscopy is universally compatible with any devices to read and is available in the digital library an online access to it is set as public so you can download it instantly.
Abstract: Thank you very much for downloading principles of fluorescence spectroscopy. As you may know, people have look hundreds times for their favorite novels like this principles of fluorescence spectroscopy, but end up in malicious downloads. Rather than reading a good book with a cup of tea in the afternoon, instead they cope with some harmful bugs inside their desktop computer. principles of fluorescence spectroscopy is available in our digital library an online access to it is set as public so you can download it instantly. Our digital library spans in multiple locations, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the principles of fluorescence spectroscopy is universally compatible with any devices to read.

2,960 citations

Journal ArticleDOI
TL;DR: In this article, the authors present the Deutsch-Jozsa algorithm for continuous variables, and a deterministic version of it is used for quantum information processing with continuous variables.
Abstract: Preface. About the Editors. Part I: Quantum Computing. 1. Quantum computing with qubits S.L. Braunstein, A.K. Pati. 2. Quantum computation over continuous variables S. Lloyd, S.L. Braunstein. 3. Error correction for continuous quantum variables S.L. Braunstein. 4. Deutsch-Jozsa algorithm for continuous variables A.K. Pati, S.L. Braunstein. 5. Hybrid quantum computing S. Lloyd. 6. Efficient classical simulation of continuous variable quantum information processes S.D. Bartlett, B.C. Sanders, S.L. Braunstein, K. Nemoto. Part II: Quantum Entanglement. 7. Introduction to entanglement-based protocols S.L. Braunstein, A.K. Pati. 8. Teleportation of continuous uantum variables S.L. Braunstein, H.J. Kimble. 9. Experimental realization of continuous variable teleportation A. Furusawa, H.J. Kimble. 10. Dense coding for continuous variables S.L. Braunstein, H.J. Kimble. 11. Multipartite Greenberger-Horne-Zeilinger paradoxes for continuous variables S. Massar, S. Pironio. 12. Multipartite entanglement for continuous variables P. van Loock, S.L. Braunstein. 13. Inseparability criterion for continuous variable systems Lu-Ming Duan, G. Giedke, J.I. Cirac, P. Zoller. 14. Separability criterion for Gaussian states R. Simon. 15. Distillability and entanglement purification for Gaussian states G. Giedke, Lu-Ming Duan, J.I. Cirac, P. Zoller. 16. Entanglement purification via entanglement swapping S. Parke, S. Bose, M.B. Plenio. 17. Bound entanglement for continuous variables is a rare phenomenon P. Horodecki, J.I. Cirac, M. Lewenstein. Part III: Continuous Variable Optical-Atomic Interfacing. 18. Atomic continuous variable processing and light-atoms quantum interface A. Kuzmich, E.S. Polzik. Part IV: Limits on Quantum Information and Cryptography. 19. Limitations on discrete quantum information and cryptography S.L. Braunstein, A.K. Pati. 20. Quantum cloning with continuous variables N.J. Cerf. 21. Quantum key distribution with continuous variables in optics T.C. Ralph. 22. Secure quantum key distribution using squeezed states D. Gottesman, J. Preskill. 23. Experimental demonstration of dense coding and quantum cryptography with continuous variables Kunchi Peng, Qing Pan, Jing Zhang, Changde Xie. 24. Quantum solitons in optical fibres: basic requisites for experimental quantum communication G. Leuchs, Ch. Silberhorn, E. Konig, P.K. Lam, A. Sizmann, N. Korolkova. Index.

2,940 citations