J
Jerry E. Manning
Researcher at University of California, Irvine
Publications - 53
Citations - 2284
Jerry E. Manning is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Gene & Trypanosoma cruzi. The author has an hindex of 29, co-authored 53 publications receiving 2244 citations. Previous affiliations of Jerry E. Manning include New York University.
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Journal ArticleDOI
Sequence arrangement of the rDNA of Drosophila melanogaster
TL;DR: The sequence arrangement of genes coding for stable rRNA species and of the interspersed spacers on long single strands of rDNA purified from total chromosomal DNA of Drosophila melanogaster has been determined by a study of the structure of rRNA:DNA hybrids.
Journal ArticleDOI
Antibody targeting of the CC chemokine ligand 5 results in diminished leukocyte infiltration into the central nervous system and reduced neurologic disease in a viral model of multiple sclerosis.
William G. Glass,Michelle J. Hickey,Jenny L. Hardison,Michael T. Liu,Jerry E. Manning,Thomas E. Lane +5 more
TL;DR: The severity of CNS disease can be reduced through the use of a neutralizing mAb directed against CCL5 in a viral model of demyelination, demonstrating the ability to differentially target select populations of T cells.
Book ChapterDOI
Gene Dosage Compensation in Drosophila Melanogaster
TL;DR: The comparative lack of sexual dimorphism of apricot and other [sex-linked] genes studied is due to "sex-limitation", i.e., to a compensatory influence of the dosage difference between the sexes in respect to other genes in the X-chromosome.
Journal ArticleDOI
Cloning of a surface membrane glycoprotein specific for the infective form of Trypanosoma cruzi having adhesive properties to laminin.
Ricardo J. Giordano,David L. Fouts,Devansu Tewari,Walter Colli,Jerry E. Manning,Maria Júlia Manso Alves +5 more
TL;DR: The hypothesis that this family encodes glycoproteins with similar sequences but differing enough as to bind to different ligands and thus forming a family of adhesion glycoprotein enabling the parasite to overcome the barriers interposed by cell membranes, extracellular matrices, and basal laminae is reinforced.
Journal ArticleDOI
CXC Chemokine Ligand 10 Controls Viral Infection in the Central Nervous System: Evidence for a Role in Innate Immune Response through Recruitment and Activation of Natural Killer Cells
Matthew J. Trifilo,Cynthia Montalto-Morrison,Linda N. Stiles,Kelley R. Hurst,Jenny L. Hardison,Jerry E. Manning,Paul S. Masters,Thomas E. Lane +7 more
TL;DR: Results indicate that CXCL10 expression plays a pivotal role in defense following coronavirus infection of the CNS by enhancing innate immune responses.