Author
Jian-Yu Pan
Other affiliations: Peking Union Medical College
Bio: Jian-Yu Pan is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Xylocarpus moluccensis & Flora. The author has an hindex of 9, co-authored 11 publications receiving 538 citations. Previous affiliations of Jian-Yu Pan include Peking Union Medical College.
Papers
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TL;DR: The mangrove flora is a diverse group of salt-tolerant plants growing in tropical and subtropical intertidal estuarine zones and the molecular phylogeny and chemotaxonomy of trueMangrove plants is discussed.
229 citations
TL;DR: This review covers the source, chemistry and bioactivities of natural lignans, and highlights the total syntheses of some lignan motifs and asymmetric synthese of their motifs.
201 citations
TL;DR: A pair of flavanone glucoside diastereomers, (2R)- and (2S)-eriodictyol-5-O-beta-d-glucopyranoside (1a, 1b), was successfully separated by RP-C(18) high-performance liquid chromatography from Balanophora involucrata Hook.
40 citations
TL;DR: Seven new phragmalins with a C-30 carbonyl moiety, named moluccensins A-G (1-7), were isolated from the seeds of an Indian mangrove, Xylocarpus moluccensis, establishing the structures of these compounds on the basis of single-crystal X-ray diffraction analysis and spectroscopic data.
Abstract: Seven new phragmalins with a C-30 carbonyl moiety, named moluccensins A-G (1-7), among which moluccensins A-F, possessing a Delta(8,14) double bond, and moluccensin G (7), containing conjugated Delta(8,9) and Delta(14,15) double bonds, were isolated from the seeds of an Indian mangrove, Xylocarpus moluccensis. The structures of these compounds were established on the basis of single-crystal X-ray diffraction analysis and spectroscopic data. This is the first report of phragmalins with a conjugated C-30 carbonyl group.
37 citations
TL;DR: Moluccensins H and I showed moderate insecticidal activity against the fifth instar larvae of Brontispa longissima (Gestro) at a concentration of 100 mg/L.
Abstract: Six new phragmalins, moluccensins H-M (1-6), two new andirobin-type limonoicls, moluccensins N and O(7, 8), and two new tirucallane derivatives, moluccensins P and Q (9, 10), were isolated from seeds of an Indian mangrove, Xylocarpus moluccensis, together with the known compound 3 beta,22S-dihydroxytirucalla-7,24-dien-23-one. The structures of these compounds were established on the basis of spectroscopic data. Moluccensins H-L were phragmalins with a C-30 carbonyl group, and moluccensin M was a unique ring-D-opened 16-norphragmalin. Moluccensins H-J possess conjugated Delta(8,9) and Delta(14,15) double bonds, moluccensins K and L contain a Delta(8,14) double bond, and moluccensin M has a characteristic C-15-C-30 linked five-membered lactone ring. Moluccensins H and I showed moderate insecticidal activity against the fifth instar larvae of Brontispa longissima (Gestro) at a concentration of 100 mg/L.
36 citations
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TL;DR: This review covers the literature published in 2014 for marine natural products, with 1116 citations referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms.
4,649 citations
TL;DR: This Perspective explores how connecting Nature's small molecules to the genes that encode them has sparked a renaissance in natural product research, focusing primarily on the biosynthesis of polyketides and non-ribosomal peptides.
Abstract: Natural products have played a prominent role in the history of organic chemistry, and they continue to be important as drugs, biological probes, and targets of study for synthetic and analytical chemists. In this Perspective, we explore how connecting Nature's small molecules to the genes that encode them has sparked a renaissance in natural product research, focusing primarily on the biosynthesis of polyketides and non-ribosomal peptides. We survey monomer biogenesis, coupling chemistries from templated and non-templated pathways, and the broad set of tailoring reactions and hybrid pathways that give rise to the diverse scaffolds and functionalization patterns of natural products. We conclude by considering two questions: What would it take to find all natural product scaffolds? What kind of scientists will be studying natural products in the future?
410 citations
TL;DR: This paper aims to demonstrate the efforts towards in-situ applicability of EMMARM, as to provide real-time information about concrete mechanical properties such as E-modulus and compressive strength.
Abstract: Natural Science Foundation of China[30000213, 30370160, 30670214]; National Basic Research Program of China (973 Program)[2009CB522300]; Chinese Academy of Sciences
372 citations
TL;DR: This review describes 564 of the latest examples of naturally occurring lignans and neolignans, and their glycosides in some cases, which have been isolated between 2009 and 2015 and highlights the biosynthesis and total synthesis of some important ones.
294 citations
TL;DR: An updated and exhaustive review of the application of counter-current chromatography, high performance liquid Chromatography, capillary electrophoresis, and their hyphenation with mass spectrometry to the study of food polyphenols is provided.
286 citations