J
Jianbin Wang
Researcher at University of Tennessee
Publications - 34
Citations - 1554
Jianbin Wang is an academic researcher from University of Tennessee. The author has contributed to research in topics: Genome & DNA. The author has an hindex of 16, co-authored 34 publications receiving 1211 citations. Previous affiliations of Jianbin Wang include University of Colorado Denver & Beijing Institute of Genomics.
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Journal ArticleDOI
ALDH1A Isozymes are Markers of Human Melanoma Stem Cells and Potential Therapeutic Targets
Yuchun Luo,Katiuscia Dallaglio,Ying Chen,William A. Robinson,Steven E. Robinson,Martin D. McCarter,Jianbin Wang,Rene Gonzalez,David C. Thompson,David A. Norris,David A. Norris,Dennis R. Roop,Vasilis Vasiliou,Mayumi Fujita,Mayumi Fujita +14 more
TL;DR: The existence of human melanoma cells that fulfill the criteria for CSCs (self‐renewal and differentiation) by serially xenotransplanting cells into nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mice is demonstrated and it is implicate that ALDH isozymes are not only biomarkers of C SCs but also attractive therapeutic targets forhuman melanoma.
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Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles
Jianbin Wang,Benjamin Czech,Amanda E. Crunk,Adam Wallace,Makedonka Mitreva,Gregory J. Hannon,Richard E. Davis +6 more
TL;DR: This work identified and characterized known and novel small RNA classes through gametogenesis and embryo development in the parasitic nematode Ascaris suum and compared them with known small RNAs of Caenorhabditis elegans, suggesting great diversification and plasticity in the use of small RNA pathways during spermatogenesis in different nematodes.
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Environmental adaptation: genomic analysis of the piezotolerant and psychrotolerant deep-sea iron reducing bacterium Shewanella piezotolerans WP3.
Fengping Wang,Jianbin Wang,Jianbin Wang,Huahua Jian,Bing Zhang,Bing Zhang,Shengkang Li,Feng Wang,Xiaowei Zeng,Lei Gao,Douglas H. Bartlett,Jun Yu,Jun Yu,Songnian Hu,Songnian Hu,Xiang Xiao +15 more
TL;DR: The genome sequence of Shewanella piezotolerans WP3, a pieZotolerant and psychrotolerant iron reducing bacterium from deep-sea sediment was determined with related functional analysis to study its environmental adaptation mechanisms.
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Complete genome sequence of bacteriophage T5
Jianbin Wang,Yan Jiang,Myriam Vincent,Yongqiao Sun,Hong Yu,Jing Wang,Qiyu Bao,Huimin Kong,Songnian Hu,Songnian Hu +9 more
TL;DR: Analysis of T5 early promoters suggests a probable motif AAA{3, 4 T}nTTGCTT{17, 18 n}TATAATA{12, 13 W}{10 R} for strong promoters that may strengthen the step modification of host RNA polymerase, and thus control transcription of phage DNA.
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Programmed DNA elimination in multicellular organisms
Jianbin Wang,Richard E. Davis +1 more
TL;DR: Recent studies provide compelling evidence that DNA elimination is a novel form of gene silencing, dosage compensation, and sex determination and further identification of the eliminated sequences, genome changes, and in depth characterization of this phenomenon in diverse metazoans are needed.