Jiang Pan

Bio: Jiang Pan is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Ceramic & Self-healing hydrogels. The author has an hindex of 8, co-authored 31 publications receiving 190 citations. Previous affiliations of Jiang Pan include Northwest Normal University.

Direct ink writing with high-strength and swelling-resistant biocompatible physically crosslinked hydrogels.

Abstract: The three-dimensional (3D) printing of hydrogels has great potential for biomedicine applications. However, it is very rare to find suitable printable materials with high strength and swelling resistance that can offer high performance. To address this challenge, this paper demonstrates the fabrication of tailored hydrogel structures by using the direct ink writing (DIW) of hybrid hydrogel inks (polyvinyl alcohol (PVA) and κ-carrageenan) with outstanding rheology. The freezing and thawing processes following DIW induce the formation of physically crosslinked networks due to the crystallinity of PVA, and thus enhance the mechanical properties and swelling resistance of the printed architectures. The resultant hydrogels exhibit excellent cytocompatibility, and most importantly, cells not only attach well to the surface of the hydrogels, but also stretch into the spaces in the grid architectures, providing appropriate microenvironments for cell culture. The physically crosslinked hydrogels, with high strength, outstanding swelling resistance, biocompatibility, and good compatibility with the DIW technique, offer many opportunities in fields such as tissue engineering, drug delivery, bone regeneration and implant medicine.

3D Printing of Dual-Physical Cross-linking Hydrogel with Ultrahigh Strength and Toughness

Abstract: 3D printing of hydrogels with high intrinsic mechanical performance has significant applications in many fields yet has been proven to be a fundamental challenge. Here, 3D printing of ultrahigh str...

Recent advances in direct ink writing of electronic components and functional devices

Abstract: Three dimensional (3D) printing technologies, known as the additive manufacturing, have been attracting extensive interests in various fields, including the academic world, industries and even daily life. It has special capabilities that can be used for increasing shape or structure complexity and fabrication efficiency, while reducing the waste materials, capital cost and design cycle for manufacturing. Among these, fabrication of functional components or devices for microelectronic systems with 3D printing technologies is still an emerging field. Recently, a series of 3D printed functional components and devices for electronics have been reported, especially with the widely used direct ink writing 3D printing. This paper will focus on materials and practical applications of 3D printing for electronic units and systems, including microelectrodes, supercapacitances, electronic circuits, batteries and so on. The implementation of 3D printing for electronics with advanced materials will have great advantage in terms of performance, microstructures, product flexibility and tailored shape along with low cost, less waste and high efficiency.

Tunneling effect in a polymer/carbon nanotube nanocompositestrain sensor

Abstract: A strain sensor has been fabricated from a polymer nanocomposite with multiwalled carbon nanotube (MWNT) fillers. The piezoresistivity of this nanocomposite strain sensor has been investigated based on an improved three-dimensional (3D) statistical resistor network model incorporating the tunneling effect between the neighboring carbon nanotubes (CNTs), and a fiber reorientation model. The numerical results agree very well with the experimental measurements. As compared with traditional strain gauges, much higher sensitivity can be obtained in the nanocomposite sensors when the volume fraction of CNT is close to the percolation threshold. For a small CNT volume fraction, weak nonlinear piezoresistivity is observed both experimentally and from numerical simulation. The tunneling effect is considered to be the principal mechanism of the sensor under small strains.

3D printing of hydrogels: Rational design strategies and emerging biomedical applications

Abstract: 3D printing alias additive manufacturing can transform 3D virtual models created by computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner dispensing with conventional molding or machining. Since the incipiency, significant advancements have been achieved in understanding the process of 3D printing and the relationship of component, structure, property and application of the created objects. Because hydrogels are one of the most feasible classes of ink materials for 3D printing and this field has been rapidly advancing, this Review focuses on hydrogel designs and development of advanced hydrogel-based biomaterial inks and bioinks for 3D printing. It covers 3D printing techniques including laser printing (stereolithography, two-photon polymerization), extrusion printing (3D plotting, direct ink writing), inkjet printing, 3D bioprinting, 4D printing and 4D bioprinting. It provides a comprehensive overview and discussion of the tailorability of material, mechanical, physical, chemical and biological properties of hydrogels to enable advanced hydrogel designs for 3D printing. The range of hydrogel-forming polymers covered encompasses biopolymers, synthetic polymers, polymer blends, nanocomposites, functional polymers, and cell-laden systems. The representative biomedical applications selected demonstrate how hydrogel-based 3D printing is being exploited in tissue engineering, regenerative medicine, cancer research, in vitro disease modeling, high-throughput drug screening, surgical preparation, soft robotics and flexible wearable electronics. Incomparable by thermoplastics, thermosets, ceramics and metals, hydrogel-based 3D printing is playing a pivotal role in the design and creation of advanced functional (bio)systems in a customizable way. An outlook on future directions of hydrogel-based 3D printing is presented.

Metal-Organic Framework-Based Hierarchically Porous Materials: Synthesis and Applications.

Abstract: Metal-organic frameworks (MOFs) have been widely recognized as one of the most fascinating classes of materials from science and engineering perspectives, benefiting from their high porosity and well-defined and tailored structures and components at the atomic level. Although their intrinsic micropores endow size-selective capability and high surface area, etc., the narrow pores limit their applications toward diffusion-control and large-size species involved processes. In recent years, the construction of hierarchically porous MOFs (HP-MOFs), MOF-based hierarchically porous composites, and MOF-based hierarchically porous derivatives has captured widespread interest to extend the applications of conventional MOF-based materials. In this Review, the recent advances in the design, synthesis, and functional applications of MOF-based hierarchically porous materials are summarized. Their structural characters toward various applications, including catalysis, gas storage and separation, air filtration, sewage treatment, sensing and energy storage, have been demonstrated with typical reports. The comparison of HP-MOFs with traditional porous materials (e.g., zeolite, porous silica, carbons, metal oxides, and polymers), subsisting challenges, as well as future directions in this research field, are also indicated.

A review on stereolithography and its applications in biomedical engineering

Abstract: Stereolithography is a solid freeform technique (SFF) that was introduced in the late 1980s Although many other techniques have been developed since then, stereolithography remains one of the most powerful and versatile of all SFF techniques It has the highest fabrication accuracy and an increasing number of materials that can be processed is becoming available In this paper we discuss the characteristic features of the stereolithography technique and compare it to other SFF techniques The biomedical applications of stereolithography are reviewed, as well as the biodegradable resin materials that have been developed for use with stereolithography Finally, an overview of the application of stereolithography in preparing porous structures for tissue engineering is given