J
Jiansheng Jiang
Researcher at National Institutes of Health
Publications - 71
Citations - 19192
Jiansheng Jiang is an academic researcher from National Institutes of Health. The author has contributed to research in topics: MHC class I & Major histocompatibility complex. The author has an hindex of 28, co-authored 60 publications receiving 18382 citations. Previous affiliations of Jiansheng Jiang include Howard Hughes Medical Institute & Brookhaven National Laboratory.
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Journal ArticleDOI
Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination
Axel T. Brunger,Axel T. Brunger,Paul D. Adams,G M Clore,W. L. DeLano,Piet Gros,R.W. Grosse-Kunstleve,R.W. Grosse-Kunstleve,Jiansheng Jiang,J. Kuszewski,Michael Nilges,Navraj S. Pannu,Randy J. Read,Luke M. Rice,Thomas Simonson,Gregory L. Warren +15 more
TL;DR: The Crystallography & NMR System (CNS) as mentioned in this paper is a software suite for macromolecular structure determination by X-ray crystallography or solution nuclear magnetic resonance (NMR) spectroscopy.
Journal ArticleDOI
Protein Data Bank (PDB): Database of Three-Dimensional Structural Information of Biological Macromolecules
Joel L. Sussman,Joel L. Sussman,Dawei Lin,Jiansheng Jiang,N.O. Manning,Jaime Prilusky,Otto Ritter,Otto Ritter,Enrique E. Abola +8 more
TL;DR: The Protein Data Bank at Brookhaven National Laboratory, is a database containing experimentally determined three-dimensional structures of proteins, nucleic acids and other biological macromolecules, with approximately 8000 entries.
Journal ArticleDOI
Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor.
Tengchuan Jin,Andrew J. Perry,Jiansheng Jiang,Patrick F. Smith,James A. Curry,Leonie Unterholzner,Zhaozhao Jiang,Gabor Horvath,Vijay A. K. Rathinam,Ricky W. Johnstone,Ricky W. Johnstone,Veit Hornung,Eicke Latz,Eicke Latz,Andrew G. Bowie,Katherine A. Fitzgerald,T. Sam Xiao +16 more
TL;DR: These findings provide mechanistic insights into dsDNA as the activation trigger and oligomerization platform for the assembly of large innate signaling complexes such as the inflammasomes.
Journal ArticleDOI
Protein hydration observed by X-ray diffraction. Solvation properties of penicillopepsin and neuraminidase crystal structures.
Jiansheng Jiang,Axel T. Brunger +1 more
TL;DR: It is hoped that site-specific radial distribution functions obtained from high-quality diffraction data will produce a picture of macromolecular solvation consistent with available experimental data and computational results.
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A Conserved Mechanism for Centromeric Nucleosome Recognition by Centromere Protein CENP-C
Hidenori Kato,Jiansheng Jiang,Bing-Rui Zhou,Marieke Rozendaal,Hanqiao Feng,Rodolfo Ghirlando,T. Sam Xiao,Aaron F. Straight,Yawen Bai +8 more
TL;DR: The findings reveal a conserved mechanism for protein recruitment to centromeres and a histone recognition mode whereby a disordered peptide binds the histone tail through hydrophobic interactions facilitated by nucleosome docking.