J
Jie Liu
Researcher at Sichuan University
Publications - 76
Citations - 1949
Jie Liu is an academic researcher from Sichuan University. The author has contributed to research in topics: Chemistry & Enantioselective synthesis. The author has an hindex of 19, co-authored 64 publications receiving 1238 citations. Previous affiliations of Jie Liu include Chinese Academy of Sciences.
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Mitochondrial Sirtuin 3: New emerging biological function and therapeutic target.
TL;DR: The intricate mechanisms of Sirtuin 3 in human diseases, and recent notable advances in the field of small-molecule activators or inhibitors targeting SIRT3 as well as their potential therapeutic applications for future drug discovery are summarized.
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Asymmetric direct aldol reaction of functionalized ketones catalyzed by amine organocatalysts based on bispidine.
Jie Liu,Zhigang Yang,Zhen Wang,Fei Wang,Xiaohong Chen,Xiaohua Liu,Xiaoming Feng,Zhishan Su,Changwei Hu +8 more
TL;DR: A theoretical study of transition structures demonstrated that protonated piperidine was important for the reactivity and enantioselectivity of this reaction.
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Catalytic Asymmetric Umpolung Allylation of Imines.
TL;DR: An iridium-catalyzed asymmetric umpolung allylation of imines is reported as a general approach to prepare 1,4-disubstituted homoallylic amines, a fundamental class of compounds that are hitherto not straightforward to obtain.
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Silver-Assisted, Iridium-Catalyzed Allylation of Bis[(pinacolato)boryl]methane Allows the Synthesis of Enantioenriched Homoallylic Organoboronic Esters
TL;DR: In this paper, an enantioselective approach of making chiral, β-substituted homoallylic organoboronic esters was described, which yielded the title compounds from allylic carbonates.
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Enantioselective Propargylation of Polyols and Desymmetrization of meso 1,2-Diols by Copper/Borinic Acid Dual Catalysis.
TL;DR: A copper/borinic acid dual catalytic reaction enabled the enantioselective propargylation of aliphatic polyols to furnish products with three stereogenic centers and a terminal alkyne group in one operation.