Jie Zhang

Bio: Jie Zhang is an academic researcher from East China University of Science and Technology. The author has contributed to research in topics: Medicine & Large Hadron Collider. The author has an hindex of 178, co-authored 4857 publications receiving 221720 citations. Previous affiliations of Jie Zhang include University of Bedfordshire & CERN.

Evidence for the H→bb¯ decay with the ATLAS detector

Abstract: A search for the decay of the Standard Model Higgs boson into a b (b) over bar pair when produced in association with a W or Z boson is performed with the ATLAS detector. The analysed data, corresp ...

Evidence for direct CP violation in B 0 → K + π - decays

Abstract: The evidence for direct charged particles (CP) violation in the decay B0→K+ π- was investigated with 253 fb-1 of data collected with the Belle detector at the KEKB e + e- collider. 275 x 106 BB pairs were used to observe a B→K±π∓ signal with 2140 ±53 events. Mixing induced CP violation in the B sector was established in b → ccs transitions. The result suggests large interference between tree and penguin diagrams and the existence of final state interactions.

I and i

Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

A new mathematical model for relative quantification in real-time RT-PCR.

Abstract: Use of the real-time polymerase chain reaction (PCR) to amplify cDNA products reverse transcribed from mRNA is on the way to becoming a routine tool in molecular biology to study low abundance gene expression. Real-time PCR is easy to perform, provides the necessary accuracy and produces reliable as well as rapid quantification results. But accurate quantification of nucleic acids requires a reproducible methodology and an adequate mathematical model for data analysis. This study enters into the particular topics of the relative quantification in real-time RT–PCR of a target gene transcript in comparison to a reference gene transcript. Therefore, a new mathematical model is presented. The relative expression ratio is calculated only from the real-time PCR efficiencies and the crossing point deviation of an unknown sample versus a control. This model needs no calibration curve. Control levels were included in the model to standardise each reaction run with respect to RNA integrity, sample loading and inter-PCR variations. High accuracy and reproducibility (<2.5% variation) were reached in LightCycler PCR using the established mathematical model.