Jie Zhang

Bio: Jie Zhang is an academic researcher from East China University of Science and Technology. The author has contributed to research in topics: Medicine & Large Hadron Collider. The author has an hindex of 178, co-authored 4857 publications receiving 221720 citations. Previous affiliations of Jie Zhang include University of Bedfordshire & CERN.

Limited access to OFDMA femtocells

Abstract: Femtocells are a promising solution for the provision of high indoor coverage and capacity. Furthermore, OFDMA-based femtocells have proven to be highly versatile when dealing with cross-layer co-channel interference thanks to the allocation of frequency subchannels. However, concerns still exist related to the impact of the different access methods to femtocells in an overlayed network. Femtocells based on a Closed Subscribers Group, where only device owners are allowed connectivity introduce severe interference to macrocell users. On the other hand, Open Access femtocells where any user can connect, does not bring many advantages to the femtocell owner. In this paper, an intermediate access method based on a limited access is proposed. The performance of the model is evaluated throughout systemlevel simulations and it is shown that limited access contributes to seriously reduce cross-layer interference while guaranteeing a minimum performance to the femtocell subscribers.

Nitric oxide: cellular regulation and neuronal injury.

Abstract: Publisher Summary A variety of mechanisms have been proposed for NO neurotoxicity, including inhibition of mitochondrial enzymes such as cis-aconitase, inhibition of the mitochondria1 electron transport chain, inhibition of ribonucleotide reductase, DNA damage, mono-adenosine diphosphate (ADP)-ribosylation, and S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase. Excessive stimulation of N-methyl-D-aspartate (NMDA) by glutamate leads to excess production of NO, which is toxic to neurons under a variety of experimental paradigms and pathological conditions. When excessive amounts of NO are formed in response to the actions of the excitatory neurotransmitter, glutamate, acting at NMDA receptors, NO mediates components of neuronal killing NMDA toxicity acting via NO may account for neural damage associated with acquired immunodeficiency syndrome (AIDS) dementia as well as neural damage in cerebral infarction. Strategies aimed at decreasing the formation of NO or identifying targets of NO'S action may have clinical relevance for the development of agents which can prevent or reverse these degenerative disorders.

Search for long-lived particles produced in pp collisions at √s = 13 TeV that decay into displaced hadronic jets in the ATLAS muon spectrometer

Abstract: A search for the decay of neutral, weakly interacting, long-lived particles using data collected by the ATLAS detector at the LHC is presented. The analysis in this paper uses 36.1 fb(-1) of proton ...

Search for resonant diboson production in the ℓℓqq̄ final state in pp collisions at √s = 8 TeV with the ATLAS detector

Abstract: This paper reports on a search for narrow resonances in diboson production in the llq (q) over bar final state using pp collision data corresponding to an integrated luminosity of 20 fb(-1) collect ...

Evidence for Higgs boson decay to a pair of muons

Abstract: Evidence for Higgs boson decay to a pair of muons is presented. This result combines searches in four exclusive categories targeting the production of the Higgs boson via gluon fusion, via vector boson fusion, in association with a vector boson, and in association with a top quark-antiquark pair. The analysis is performed using proton-proton collision data at $ \sqrt{s} $ = 13 TeV, corresponding to an integrated luminosity of 137 fb$^{−1}$, recorded by the CMS experiment at the CERN LHC. An excess of events over the back- ground expectation is observed in data with a significance of 3.0 standard deviations, where the expectation for the standard model (SM) Higgs boson with mass of 125.38 GeV is 2.5. The combination of this result with that from data recorded at $ \sqrt{s} $ = 7 and 8 TeV, corresponding to integrated luminosities of 5.1 and 19.7 fb$^{−1}$, respectively, increases both the expected and observed significances by 1%. The measured signal strength, relative to the SM prediction, is $ {1.19}_{-0.39}^{+0.40}{\left(\mathrm{stat}\right)}_{-0.14}^{+0.15}\left(\mathrm{syst}\right) $. This result constitutes the first evidence for the decay of the Higgs boson to second generation fermions and is the most precise measurement of the Higgs boson coupling to muons reported to date.[graphic not available: see fulltext]

I and i

Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

A new mathematical model for relative quantification in real-time RT-PCR.

Abstract: Use of the real-time polymerase chain reaction (PCR) to amplify cDNA products reverse transcribed from mRNA is on the way to becoming a routine tool in molecular biology to study low abundance gene expression. Real-time PCR is easy to perform, provides the necessary accuracy and produces reliable as well as rapid quantification results. But accurate quantification of nucleic acids requires a reproducible methodology and an adequate mathematical model for data analysis. This study enters into the particular topics of the relative quantification in real-time RT–PCR of a target gene transcript in comparison to a reference gene transcript. Therefore, a new mathematical model is presented. The relative expression ratio is calculated only from the real-time PCR efficiencies and the crossing point deviation of an unknown sample versus a control. This model needs no calibration curve. Control levels were included in the model to standardise each reaction run with respect to RNA integrity, sample loading and inter-PCR variations. High accuracy and reproducibility (<2.5% variation) were reached in LightCycler PCR using the established mathematical model.