J
Jie Zheng
Researcher at Washington University in St. Louis
Publications - 37
Citations - 2216
Jie Zheng is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 24, co-authored 31 publications receiving 2036 citations. Previous affiliations of Jie Zheng include Northwestern University.
Papers
More filters
Journal ArticleDOI
3D MRI-based multicomponent FSI models for atherosclerotic plaques
Dalin Tang,Chun Yang,Jie Zheng,Pamela K. Woodard,Gregorio A. Sicard,Jeffrey E. Saffitz,Chun Yuan +6 more
TL;DR: The authors' results indicate that large lipid pools and thin plaque caps are associated with both extreme maximum (stretch) and minimum (compression when negative) stress/strain levels, which may lead to artery fatigue and possible plaque rupture.
Journal ArticleDOI
Sites of Rupture in Human Atherosclerotic Carotid Plaques Are Associated With High Structural Stresses An In Vivo MRI-Based 3D Fluid-Structure Interaction Study
Dalin Tang,Zhongzhao Teng,Gador Canton,Chun Yang,Marina S. Ferguson,Xueying Huang,Jie Zheng,Pamela K. Woodard,Chun Yuan +8 more
TL;DR: Plaques with prior ruptures are associated with higher critical stress conditions, both at ulcer sites and when compared with nonruptured plaques, and plaque stress analysis may provide additional stress indicators helpful for image-based plaque vulnerability assessment.
Journal ArticleDOI
Local maximal stress hypothesis and computational plaque vulnerability index for atherosclerotic plaque assessment.
Dalin Tang,Chun Yang,Chun Yang,Jie Zheng,Pamela K. Woodard,Jeffrey E. Saffitz,Joseph D. Petruccelli,Gregorio A. Sicard,Chun Yuan +8 more
TL;DR: The initial results based on 34 2D MRI slices from 14 human coronary plaque samples indicate that CPVI plaque assessment has an 85% agreement rate (91% if the square root of stress values is used) with assessment given by histopathological analysis.
Journal ArticleDOI
Quantifying Effects of Plaque Structure and Material Properties on Stress Distributions in Human Atherosclerotic Plaques Using 3D FSI Models
Dalin Tang,Chun Yang,Jie Zheng,Pamela K. Woodard,Jeffrey E. Saffitz,Gregorio A. Sicard,Thomas K. Pilgram,Chun Yuan +7 more
TL;DR: Effects caused by atherosclerotic plaque structure, cap thickness and erosion, material properties, and pulsating pressure conditions on stress/strain distributions in the plaque are quantified by extensive computational case studies and parameter evaluations.
Journal ArticleDOI
Effect of Stenosis Asymmetry on Blood Flow and Artery Compression: A Three-Dimensional Fluid-Structure Interaction Model
TL;DR: The results indicate that severe stenosis causes critical flow conditions, high tensile stress, and considerable compressive stress in the stenosis plaque which may be related to artery compression and plaque cap rupture.