J
Jiean Chen
Researcher at Peking University
Publications - 44
Citations - 880
Jiean Chen is an academic researcher from Peking University. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 12, co-authored 34 publications receiving 687 citations.
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Journal ArticleDOI
Rhodium(III)-catalyzed C-H activation of arenes using a versatile and removable triazene directing group.
TL;DR: This method exhibits substantial post-functionalization synthetic versatility, overcoming a vital limitation in C sp 2-H activation/functionalization products: restricted structural diversity.
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Highly enantioselective sulfa-Michael addition reactions using N-heterocyclic carbene as a non-covalent organocatalyst
TL;DR: Enantioselective asymmetric sulfa-Michael addition (SMA) reactions using a chiral N-heterocyclic carbene as a non-covalent organocatalyst.
Journal ArticleDOI
Asymmetric catalysis with N -heterocyclic carbenes as non-covalent chiral templates
Jiean Chen,Yong Huang +1 more
TL;DR: It is found that catalytic amounts of hexafluoroisopropanol are the critical proton shuttle that facilitates hydrogen transfer to provide high-reaction rates and high enantioselectivity and it is demonstrated that a successful asymmetric reaction of this type can be accomplished through a rational design that balances the pKa values of the substrate, the carbene precursor and the product.
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Highly Enantioselective Aza‐Michael Reaction between Alkyl Amines and β‐Trifluoromethyl β‐Aryl Nitroolefins
TL;DR: The use of chiral N-heterocyclic carbenes as noncovalent organocatalysts are reported to promote a highly selective aza-Michael reaction between primary alkyl amines and β-trifluoromethyl β-aryl nitrooleolefins.
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Enantioselective β-Protonation of Enals via a Shuttling Strategy
TL;DR: A shuttling system that delivers a proton in a highly enantioselective manner to the β-carbon of enals using a chiral N-heterocyclic carbene (NHC) catalyst and regeneration of the NHC catalyst results in functionalization of the carbonyl group.