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Jiefei Geng

Researcher at Harvard University

Publications -  32
Citations -  13591

Jiefei Geng is an academic researcher from Harvard University. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 22, co-authored 31 publications receiving 11682 citations. Previous affiliations of Jiefei Geng include Life Sciences Institute & University of Michigan.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

The Atg8 and Atg12 ubiquitin‐like conjugation systems in macroautophagy

Jiefei Geng, +1 more
- 01 Sep 2008 - 
TL;DR: The main characteristic of autophagy is the formation of a double‐membrane vesicle, the autophagosome, which envelops part of the cytoplasm and delivers it to the lysosome/vacuole for breakdown and eventual recycling of the degradation products.
Journal ArticleDOI

SNARE proteins are required for macroautophagy

Usha Nair, +15 more
- 22 Jul 2011 - 
TL;DR: Evidence is provided for the involvement of exocytic Q/t-SNAREs in autophagosome formation, acting in the recruitment of key autophagy components to the site of autophagic formation, and in regulating the organization of Atg9 into tubulovesicular clusters.
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Activation of Necroptosis in Multiple Sclerosis

Dimitry Ofengeim, +19 more
- 24 Mar 2015 - 
TL;DR: It is shown that necroptosis mediates oligodendrocyte degeneration induced by TNF-α and that inhibition of RIPK1 protects against oligod endodermal cell death in two animal models of MS and in culture.