J
Jing Wang
Researcher at Georgia Regents University
Publications - 96
Citations - 2523
Jing Wang is an academic researcher from Georgia Regents University. The author has contributed to research in topics: Neuroprotection & Retinal. The author has an hindex of 22, co-authored 86 publications receiving 1757 citations. Previous affiliations of Jing Wang include Discovery Institute & Chinese Academy of Sciences.
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Journal ArticleDOI
NADPH oxidase in brain injury and neurodegenerative disorders.
Merry W. Ma,Merry W. Ma,Jing Wang,Jing Wang,Quanguang Zhang,Quanguang Zhang,Ruimin Wang,Ruimin Wang,Krishnan M. Dhandapani,Krishnan M. Dhandapani,Ratna K. Vadlamudi,Darrell W. Brann,Darrell W. Brann +12 more
TL;DR: Evidence supporting the role of NADPH oxidase in the pathology of neurodegenerative disorders is summarized, pharmacological strategies of targeting this major oxidative stress pathway are explored, and obstacles that need to be overcome are outlined for successful translation of these therapies to the clinic.
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Neuron-Derived Estrogen Regulates Synaptic Plasticity and Memory.
Yujiao Lu,Gangadhara R. Sareddy,Jing Wang,Ruimin Wang,Yong Li,Yan Dong,Quanguang Zhang,Jinyou Liu,Jason C. O'Connor,Jianhua Xu,Ratna K. Vadlamudi,Darrell W. Brann +11 more
TL;DR: Direct genetic evidence of a critical role for neuron-derived E2 in the regulation of rapid AKT-ERK and CREB-BDNF signaling in the mouse forebrain is provided and demonstrates that neuron- derived E2 is essential for normal expression of LTP, synaptic plasticity, and cognitive function in both the male and female brain.
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Enantioselective assembly of substituted dihydropyrones via organocatalytic reaction in water media.
TL;DR: The diarylprolinol ether/HOAc-catalyzed cascade Michael addition and cyclization of aldehydes and alpha-keto-alpha,beta-unsaturated esters proceeds smoothly in water to afford cyclic hemiacetals, which are oxidized to furnish highly functionalized 3,4,5,6-tetrasubstituted dihydropyrones with excellent enantioselectivities.
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Sigma 1 Receptor regulates the oxidative stress response in primary retinal Müller glial cells via Nrf2 signaling and system xc−, the Na+-independent glutamate-cystine exchanger
Jing Wang,Arul Shanmugam,Shanu Markand,Eric P. Zorrilla,Vadivel Ganapathy,Sylvia B. Smith,Sylvia B. Smith +6 more
TL;DR: It is concluded that Müller glial cells lacking σ1R manifest elevated ROS, perturbation of antioxidant balance, suppression of NRF2 signaling, and impaired function of system xc(-, the cystine-glutamate exchanger important for synthesis of glutathione).
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Single atom Ru doping 2H-MoS2 as highly efficient hydrogen evolution reaction electrocatalyst in a wide pH range
TL;DR: In this paper, single-atom ruthenium-doped molybdenum disulfide with high 2H phase content (Ru@2H-MoS2) catalysts are synthesized by a two-step hydrothermal method.